The Role of the Pituitary Gonadotropins 



17 



Another luteinizing substance, human chorionic gonadotropin (HCG), was 

 tested as a supplement at levels from 2 to 32 lU (Table 18, RU = HJ). Doses 

 of 8 or more lU HCG were found to be effective as ovulatory supplements 

 following combinations of 2 RU FSH + 8 RU ICSH. The results were the 

 same when 10% intrinsic ICSH was present in the FSH preparation, but 

 following FSH containing 4% ICSH higher doses of HCG were required, 

 32 lU being optimal (Table 18). 



The importance of the presence of more than4 % ICSH with the FSH during 

 stimulation of follicular growth was exemplified further by experiments 



Table 19. Graded Doses of ICSH as the Ovulatory Supplement, after Follicular 

 Development by Purified FSH, with or without the ADomoN of 10% ICSH 



Not counted ; distended oviducts. 



Table 20. Graded Doses of HCG as the Ovulatory Supplement, after Follicular 

 Development by Purified FSH, with or without the Addition of 10% ICSH 



* Not counted; distended oviducts. 



