Discussion 23 



We conclude from these observations that LH preparations of non-primate origin 

 are capable of stimulating the interstitial cells of the hypophyscctomized male monkey 

 with resultant increases in androgen secretion. While preliminary evidence indicates 

 that quantitative differences may exist in the potencies of various LH preparations in 

 the monkey, an absolute species specificity analogous to that described for growth 

 hormone cannot be attributed to FSH and LH, at least as far as the monkey is con- 

 cerned. The difficulties encountered in experimental ovulation in primates must 

 reside, as Dr. Simpson has so clearly indicated, in problems concerned with the 

 dosages and ratios of the hormones used as well as the timing of their administration. 



