202 



Carl A. Gemzell 



excretion and the secretory reaction of the endometrium. The elevated 

 level of urinary pregnanediol lasted for about two weeks and a menstrual 

 bleeding occurred when the excretion ceased. 



Pi 



Cose A S Age 25yMr 



FSH (lOmg/d) 



liiilliill 



HCG(6000lU/d) 

 Estrone (>jg/48hrs) n 



30h Estriol (>jg/48hrs) 

 20 



8_i Pregnonediol (mg/48hrs) 

 6 



30J T7-KS (mg/48hrs) 

 20 



Endometriol Activity 

 P (0) S 



18/-, 



"3 30/3 10/4 



Fig. 6. Urinary excretion of estrogen, pregnanediol, 17-corticosteroids and 17-ketosteroids 

 before and following the administration of FSH and HCG. The patient was operated upon 



April 1st. 



The effect of FSH seemed to be a function of time. Following a 20-day 

 treatment with human pituitary FSH in a 28-year-old woman with secondary 

 amenorrhea, the ovaries reached a diameter of 12 to 15 cm and the urinary 



