232 



John Rock 



worker who at fust said thai she took all the tablets but later, when the 

 figures were brought to her attention, admitted that she may have forgotten 

 some. 



When patients missed tablets, follicles were sometimes ready to rupture, 

 and not much of a release was required to enable some of them to do so. 



Table 8. Fertility Control with Enovid: Mean Frequency of Coitus Reported 

 PER Month in Premedication and Medication Cycles 



Table 9. Fertility Control with Enovid: Pregnancy Rates according to Number 



OF Pills Missed vs. Postmedication Pregnancy Rate 



(All Projects Combined: Data Tabulated as of November, 1959) 



* Pregnancy rate per 100 woman-years. 



There were some 1500 cycles in which medication was intermittent. In the 

 group in which tablets were omitted on not more than 5 days, 4 pregnancies 

 occurred. There were 14 pregnancies when medication was missed on more 

 than 5 days. 



V. OTHER EFFECTS OF ENOVID 

 A. Effects on the Menstrual Cycle 



1. Cycle length. One almost indispensable clinical quality in an ovulation- 

 suppressant is its capability to be used effectively without disrupting the 



