330 



I miliiiilj' do BOt CQBSvKr it ci]ie omIx aod xL>o 

 of Ag y.«!tki>t tp egphjn w lwj cw i ii. iadactitMt i,S^e 

 finan I>eBe«r« HI L> Howek^r, so f jut ^ ead bt T oak mflac^ 

 part of Alt gsnenl |M cl4 e » of snie actni aad so-cdkd 

 > B wrtMi Ae spbeae <rf i i fcui ' ^ ctf Ae yetkaSt I far oae 

 AM v«ni- sbeplkal ii i«9Mrd to ^ iMbodbcftmi of tt» wobbKr coBCCi>t 

 of tie 1 1 1 I i iR i Ml . wA fe ■gratePWB cw i mwtaw i s — d « lec<iiM B> aJl 

 off vkkii BHSt talae plate ainailDasljr a de KWfMud oider and in 

 Aie pmper pbce to aBomr a fnfaaa^riytini o£ die facts of piog:n?ssi\>f> 

 deteoMMtioa ia teoK of co^vstdes. 1 rawnt lel(p disagroc ing widi 

 sack oeat wa l a5 < > lc M BBts as EbraclKt ^id Hollfireter in diis nqpeci. 



Actaa!h\ there m&iy be rmTce p^asoa far peggBaraa m legaid Id die 

 fijl i h' ■ of gtj i m% coatiolied che ■i wlifc ■ w aliili o ai of tie cy topfcw i air 

 i^ inaaeane Iwdr of iahii iliiig bfodKaakal facts kas 

 oa tie dKaaieal processes in emfanrogenesis* vidi 

 ■sjjJKjaa^ to ■ e al i o a oai^ die vori: of 

 las schooi. l.BidaMi Baaoi. Spfe gci a M m^ and 

 tikese iMJliaafr leseavdms stop to look at tbe gmeral 

 dctived fraaa tjae detaaed fads^ ™^ draw oobcmsiobs wukxi 

 deadhr 4e canses for aqr pessaasBL Tins is best sivmii b>- 

 : fraaa a leoeat s >yaop M5. Inr HoltiB (19^), in wiadi be presents 

 of die netabofie bafrginwian ck detenHaatiaa ia 

 tbe eadNr devefapaaeat of die sea orebaa egg;: ""Ibe ea^ devebjpneat 

 ■ay be iu ft Lipntid as a gadndL Matraceffldbr transfonaatioB of a snp- 

 plr of sobsftaaces of piaebr naieraal ongjn iato nKtabolar oeaba and 

 netabofic prodacts of tbe nev iadlvidaal anbt^niL 



""'ibe lapadhr increasiBg piotcin metuboasBi in die nacrasoaae 

 Ikacti na duU a g tbe easijr sea vidaa li m bf— irf naay indicato die 

 of a progiressrre biriitteac op of mfci o soa ae popQfaitiQn& Tbe 

 dboandeotide netabobsaB dnriag; die detennma^ion peiiod 

 wtfb sacb aa jatopietatiiaii 

 the BesencbjnaK bJastwh stage popofaedoos of De\viy 

 iim M cd —BhiilMMH^ii appear. Ibis is i n d ic a le d ako in isotope esperi- 

 hr aa i a ucas e d aeldbofie lato in die pi o t e i ns of tbe mfto- 

 bnctioa. ^obabljr die new a a to tboa d iia popoktions are 

 ap fitoaa cotaia kiads of sobaacrasoopic gnaales ... As a 

 of die i Bc aeased "^SfcuifcMiili^ deasftr^ whicb is first 

 tbe aaanal legiQaL a senes of encmnes> associated widi 

 actinttes, amd die aaano acid metabc^- 

 UtOKCOvcr die iVimmK for pbospbate-boad exKrg>' 



