VETERINARY MEDICINE. 27Y 



aunual has been previously uoted (E. S. R., 28. p. 178). The contents of the 

 present volume are as follow^s : Pathology of Cancer, by G. Herxheimer and F. 

 Reiiike (pp. 1-343) ; Itegeneration, Transplantation, and I'arabiosis. by M. 

 (ioldzieher and E. Makai ipp. 344-759) ; and the Histological Detection and 

 Biochemical Siguilicance of Oxidizing and Reducing Substances Within the Cell, 

 by W. Loele (pp. 7(;0-80G). 



A large bibliography accompanies each topic. 



Studies fronx the Rockefeller Institute for Medical Research (Studies 

 Rockefeller lufit. Med. Research, 18 (J914), pp. ¥11+596, pis. 77, figs. 22).— This 

 is a collection in one volume of the studies which have appeared from time to 

 time in the literature from the departments of pathology and bacteriology, 

 physiology and jiharmacology, chemistry, experimental surgei'y, experimental 

 biology, and the hospital of the Rockefeller Institute. 



The Lister Institute of Preventive Medicine (Lister Inst. Prer. Med., Col- 

 lected Papers, No. 9, pt. 2 (1912-13), pp. [TZ+.-J-^O], ph. 20, figs. .1'/).— This is 

 a collection of reprints of articles on physiology, zoology, and biochemistry pub- 

 lished in various scientific journals. 



Blood sugar, I. Bang (Der Blutzucker. Wiesbaden, 1913, pp. VIII -{-162, figs. 

 13). — This exceptional volume deals with the physiological sugar content of the 

 blood of man, bovine, horse, sheep, goat, pig, rabbit, cat, and other animals, the 

 reducing substances in blood and their distribution, physiological variation of 

 the sugar content of the blood, experimental hyperglyconna and hypoglycemia, 

 the origin of sugar in the blood, and historical facts relating thereto. 



Anaphylaxis, C Richet, trans, by J. M. Bligh (Liverpool and London, 191S, 

 pp. XII+2G6). — An English translation of this work. Among the topics dis- 

 cussed are the history of anaphylactic phenomena, duration and symptoms of 

 jinaphylaxis, anaphylactizing substances, passive anai)hylaxis. anaphylaxis in 

 vitro, the relation of anaphylaxis to the precipitin and the complement devia- 

 tion reactions, antinnaiihylaxis. anaphylaxis in medicine, and local, chronic, 

 alimentary, and general anaphj'laxis. 



Studies on the complementary and antihemolytic properties of normal 

 sheep serum, F. M. Surface and G. C. Routt (Jour. Med. Research, 2S (1913). 

 No. 3, pp. Jtkl-463). — '' Fresh normal sheep serum contains a complement capable 

 of dissolving sensitized sheep corpuscles. Sheep serum is relatively poor in 

 hemolytic complement. It rapidly loses its complement ability upon standing. 

 Fresh normal sheep serum is able to prevent the action of guinea pig complo- 

 ment. In the fresh serum this inhibiting property is partially masked by the 

 native complement in the sheep serum. If the sheep serum is heated just suffi- 

 ciently to destroy its complement the inhibiting property remains and can be 

 clearly demonstrated. 



" Heating the sheep serum to temperatures below 52° C. increases its inhibit- 

 ing properties. Heating at temperatures higher than this tends to destroy this 

 property. If the serum is heated to 60° or beyond, both its complement and its 

 antihemolytic property are destroyed. There is an apparent auxilytic action 

 of the guinea pig complement upon the comr>lement of the sheep serum. This 

 inhibiting property of sheep serum is not due to complement fixation by anti- 

 bodies in the hemolytic rabbit serum. It is probably not due to any precipitate 

 which may be formed by the mixture of guinea pig and sheep serum. 



" The evidence indicates that there is a true anticomplement (against guinea 

 pig complement) in fresh normal sheep serum. This is present in relatively 

 small amounts, and most of its action is masked by the sheep complement. 

 If the complement is removed from the sheej) serum the anticomplement be- 

 comes manifest. The anticomplement is destroyed by heating at 60° and higher. 



