VETEKINARY MEDICINE. 877 



a rapid rise of the leucocytes which falls back rapidly. This increase in leuco- 

 cytes is independent of the rise in temperature. Apparently the sera act 

 specifically upon the leucocyte-producing organs. 



Serodiagnosis according to Abderhalden, Allmann {Deut. Med. Wchnschr., 

 40 (1914), No. 6, pp. 271-274). — With pregnant subjects the results were uni- 

 formly positive and in myoma negative. With carcinoma of the genitals and 

 other inflammations the results were questionable. 



Adsorption phenomena in the Abderhalden dialysis method, F. Plaut 

 {Munchen. Med. Wchnschr., 61 {1914), ^0. 5, pp. 238-241) .—The presence of 

 Inorganic substances incapable of cleaving iDroteins by themselves, such as talc, 

 barium sulphate, and infusorial earth, was found to produce an increase of 

 substances in the dialyzate which gave the ninhydriu reaction. 



The cases which were in man were mostly nervous disorders. 



About the specificity of Abderhalden's dialysis method, H. Singer 

 (Munchen. Med. Wchnschr., 61 (1914), No. 7, pp. 350-352) .—The results show 

 that if the blood of healthy male rabbits is injected intravenously or subcu- 

 taneously into the same or another kind of animal, ferments are elaborated 

 which shortly after will cleave rabbit placenta, liver, and muscle tissue. The 

 same results were obtained with a man who received his own serum intra- 

 venously from one to two hours after drawing. 



The ferments present in the body are said to be " groupe specific." 



Notes about the utility of the dialyzing method in clinical and biological 

 questions, E. Abdeehalden {Miinchen. Med. Wchnschr., 61 {1914), No. 5, pp. 

 233-238, fig. 1). — In this article the author points out some of the reasons for 

 the inconcordant results obtained by the Abderhalden method. 



It often happens that about 50 per cent of the dialyzing thimbles (diffusion 

 shells) sold are faulty inasmuch as they allow the passage of undeuaturized 

 protein. Some of the shells are especially sensitive toward boiling water. 

 The biuret test is preferred for the natural protein while the ninhydrin test 

 is recommended for the cleavage products. The test may also be conducted 

 by removing the undigested protein with precipitating reagents or with the 

 ultrafllter of Bechhold. 



A second source of error in the method is the use of an unsatisfactory sub- 

 stratum. The substratum must above all things be free from blood and dif- 

 fusible products. The results obtained from organs other than placenta and 

 tissues from pathological cases are discussed. When the method is used for 

 diagnosing tumors or cancers, only the specific substratum should be used. 

 Organs from another species of animals may eventually be used, but as our 

 state of knowledge in this direction is not complete, it is advisable to use only 

 species specific organs. 



The work of other authors is critically discussed, and it is emphasized that 

 when the results with the method are reported they should be accompanied by 

 the other clinical fin<iings. 



The serodiagnosis of infectious diseases with the aid of Abderhalden's 

 dialyzing method, E. Voelkel {Miinchen. Med. Wchnschr., 61 {1914), ^o- 7, 

 pp. 349, 350). — This describes tests made with diphtheria, anthrax, and typhoid 

 bacteria, nagana trypanosomes, and Spirochceta pallida as substrata for diag- 

 nosing the respective diseases caused by the organisms named. 



Satisfactory results were obtained with typhoid bacilli and S. pallida, and in 

 some cases with the serum protein of luetic subjects. The complement fixation 

 (Wassermann's reaction) showed positive in almost every case in which the 

 dialysis method showed the same condition. All luetic sera protein can not 

 be used for the dialysis test. 



