200 KARL G. LARK 



tihifting the balance of control to emphasize either i)roliferation or func- 

 tion. The control of DNA biosynthesis may thus present the key to the 

 problem of cellular (lifferentiation. 



Acknowledgments 



The autlior wishes to thank Drs. R. Okazaki and J. Paul for making available 

 their results prior to publication. He is indebted to Drs. V. Bonifas, H. Stern, 

 L. J. Tolmach, and P. M. B. Walker for their comments on the manuscript. 

 Unpublislied work of the author, presented above, was sujjported by grant E-1391 

 of the National Institutes of Health, Bethcsda, Maryland. 



References 



Abbo, F. E., and Pardee, A. B. (1960). Biochim. el Biophys. Acta 39, 478. 



Alfert, M. (1955). Stjmpofsiuni oti Fine Struclure of Cells, Leiden, 1054, p. 157. 



Alfert, M., and Das, N. K. (1961). Proc. Am. Soc. Cell. Biol. 1, 6. 



Aronson, A. I., and Spiegelman, S. (1961a). Biochim. et Biophys. Acta 70, 70. 



Aronson, A. I., and Spiegelman, S. (1961b). Biochim. et Biophys. Acta 70, 85. 



Astrachan, L., and Volkin, E. (1958). Biochim. et Biophys. Acta 32, 449. 



Baddiley, J., and Blumson, N. L. (1960). Biochim. et Biophys. Acta 39, 376. 



Barner, H. D., and Cohen, S. S. (1956). J. Bacteriol. 72, 115. 



Barner, H. D., and Cohen, S. S. (1957). J. Bacteriol. 74, 350. 



Barnum, C. P., Jardetzky, C. D., and Halberg, F. (1957). Texas Repts. Biol. Med. 



15, 135. 

 Bessman, M. J., Lehman, I. R., Simms, E. S., and Romberg, A. (1958). J. Biol. 



Chem. 233, 171. 

 Bianchi, P. A., Crathorn, A. R., and Shooter, K. V. (1961). Pruc. Intern. Congr. 



Biophys., Stockholm, 1061, p. 230. 

 Billen, D. (1959a). Nature 184, 174. 

 Billen, D. (1959b). Biochim. et Biophys. Acta 34, 110. 

 Billen, D. (1960a). Nature 187, 1044. 

 Billen, D. (1960b). J. Bacteriol 80, 86. 

 Billen, D. (1961). Pathol. Biol. 9, 758. 

 Billen, D. (1962a). Biochim. et Biophys. Acta, in i)ress. 

 Billen, D. (1962b). Biochem. Biophys. Research Communs. 7, 173. 

 Bloch, D. P. (1958). In "Frontiers in Cytology" (S. L. Palay, ed.), p. 113. Yale 



Univ. Press, New Haven, Connecticut. 

 Bloch, D. P., and Godman, G. C. (1954). J. Histochem. and Cytochem. 2, 455. 

 Bloch, D. P., and Godman, G. C. (1955). J. Biophys. Biochem. Cytol. 1, 17. 

 Bojarski, B., and Hiatt, H. H. (1960). Nature 188, 1112. 

 BoUum, F. J., and Potter, V. R. (1959). Cancer Research 19, 561. 

 Bollum, F. J., Andregg, J. W., McElya. A. B., and Potter, V. R. (1960). Cancer 



Research 30, 138. 

 Bonner, J., Huang, R. C, and Maheshwari, M. (1961). Proc. Natl. Acad. Sci. U.S. 



47, 1548. 

 Brenner, S., Jacob, F., and Meselson, M. (1961). Nature 190, 576. 

 Britten, R. J., McCarthy, B. J., and Roberts, R. B. (1962). Biophys. J. 2, 83. 

 Brody, S., and Balis, M. E. (1959). Cancer Research 19, 538. 

 Bucher, N. R. L., and Mazia. D. (1960). J. Biophys. Biochem. Cytol. 7, 651. 

 Bucher, N. R. L., Scott, J. E., and Aub, J. C. (1951). Cancer Research 11, 457. 



