SUBJECT INDEX 



543 



Phosphorylase, polynucleotide, 280 

 Phosphorylation of deoxATibonucleotides, 



12-16 

 Photod\'namic effect of dyes, 225 

 Point mutation, 214 

 Polymerase, DXA, 



bacteriophage-specific, 54-56 



calf thymus, 50-54 



E. coli. 17-21. 40-45 

 Polymerase, RXA, 280-281 

 PohTiucleotides, synthetic, 280 



use in coding studies, 282-285 

 Pools, metabolic, 311-314 

 Primer as a factor in controlling DXA 



replication, 181-183 

 Proflavin, mutagenic effect of, 224, 239 

 Protein s^mthesis, 353-400 



final stages of, 378-381 



kinetics of incorporation of label, 331- 

 333 



requirement for DXA replication, 178- 

 179 



sequence of bond formation, 374-378 

 P^Tophosphorolysis, 21 



Radiation, indirect effects in mutation 



studies. 242 

 Radiations, ionizing, mutagenic effect of, 

 240-243 

 ultraviolet light, mutagenic effect of. 

 243-245 

 Recombination, genetic. 82-88 



mechanism of. 87, 96. 107, 132, 137 

 X phage DXA, 86-87 

 Replication, see DNA replication 

 Revertants, 254 

 Ribonucleic acid (RXA) 

 bios^-nthesis of, 272-286, 326-331. 335- 



341 

 DX\A.-like, 273 



RXA, homologous to DXA, 275 

 messenger, 275-276, 344, 382-386 



isolation of, 279 

 soluble (see also transfer RXA), 368- 



369 

 sj-nthesis of, 271-286 



cell free s^^stems, 397-400 

 DXA-directed, 281, 386-390, 39&-397 



relation to DXA SA-nthesis, 186-188 

 T2-specific, 274 

 turnover of, 275-276 



upon phage infection, 278 

 Ribosomes, 292-350 

 assembly of, 333 

 effects of chloramphenicol, 298 



of magnesium on, 293-296 

 fractionation of, 308-310 

 nucleic acid components of, 305-306 

 protein-RX'A ratio, 300-302 

 protein components, 302-303 

 purification of, 299-302 

 site of protein s^Tithesis, 299 

 stnicture of, 295, 306-307 

 s>-nthesis of, 321-350, 395-396 



site of, 346, 363-367 

 Ribotides, conversion to deoxjTibotides, 



169-170 



Sedimentation analysis, see Gradient 



centrifugation 

 Serine as methyl donor, 7 

 Sulfur mustard, see Alky'lating agents 



Target theor>-, 241 

 Tetrahydrofolic acid, 7-9 

 Thalassemia. 450-453 



genetics of, 450 

 Thymidine-H", 74-76 

 Thymidine kinase, 13 

 Thymidylate kinase, 13 

 Thymidylic acid, 6-10 



SA-nthesis of, 6-10 

 Tobacco mosaic virus (TMV) 477-517 



t:mv, 



amino acid composition, 493-495 

 infectivity. 489-491 

 protein, 484-489 



amino acid sequence. 486 

 protein composition of mutants, 499- 



508 

 ribonucleic acid. 487-489 

 structure of. 479-483 

 SATnptomatology. 491-493 

 virulence and viability, 508-509 



