Ki2 CHAPTER 1] 



REFERENCES 



^uerbach, C, Mutation. An Introduction to Research on Mutagenesis. Part I. Meth- 

 ods, Edinburgh: Oliver and Boyd, 1962. 



Blakeslee, \. I .. "New Jimson Weeds from Old Chromosomes," J. Hered., 25:80 108, 

 1934. 



Blakeslee, \. I . and Belling, J., "Chromosomal Mutations in the Jimson Weed. Datura 

 Stramonium," J. Hered., 15:194 206, l l >24. 



Bridges, C. G., and Brehme, K. S., The Miliums oj Drosophila Melanogaster, Wash- 

 ington. D.C.: Carnegie Institution of Washington, Publ. 552. 1944. 



Burdette, W. J. (Ed.). Methodology in Mammalian Genetics, San Francisco: Holden- 

 Day, Inc.. 1963. 



Dobzhansky, lh.. Genetics and the Origin of Species, 2nd Ed.. New York: Columbia 

 University Press. Chap. 7. pp. 223-253. 1941. 



Griffen, A. B., and Bunker. M. C. "Three Cases of Trisomy in the Mouse." Proc. Nat. 

 Acad. Sci.. U.S.. 52:1194-1198. 1964. 



Heitz. E.. and Bauer. H., "Beweise fiir die Chromosomennatur der Kernschleifen in 

 den Knauelkernen von Bibio hortulanus L. (Cytologische Untersuchungen an 

 Dipteren, 1)." Z. Zellforsch.. 17:67-82. 1933. 



Painter. T. S.. "A New Method for the Study of Chromosome Rearrangements and 

 Plotting of Chromosome Maps," Science, 78:585-586, 1933. Reprinted in Classic 

 Papers in Genetics, Peters. J. A. (Ed.), Englewood Cliffs, N.J.: Prentice-Hall, 

 pp. 161-163. 1959. 



Patau, K.. Smith. D. W.. Therman, E., Inhorn. S. L., and Wagner, H. P., "Multiple 

 Congenital Anomaly Caused by an Extra Autosome." Lancet, 1:790-793, 1960. 



Russell. L. B.. "Chromosome Aberrations in Experimental Mammals," Progress in 

 Medical Genetics. 2:230-294. 1962. 



Steffensen, D. M.. "Evidence for the Apparent Absence of DNA in the Interbands of 

 Drosophila Salivary Chromosomes." Genetics, 48:1289-1301, 1963. 



Suomalainen, E.. "Significance of Parthenogenesis in the Evolution of Insects," Ann. 



Rev. Ent., 7:349-366, 1962. 

 White. M. J. D.. Animal Cytology and Evolution, 2nd Ed.. Cambridge: Cambridge 



University Press. 1954. 



QUESTIONS FOR DISCUSSION 



11.1. How do we know that the genetic differences in a population today were not 

 always present? 



11.2. What have you learned in this chapter about the characteristics of mutation? 



11.3. What is the relation between mutants and genes? Mutants and recombination? 



11.4. From your present knowledge, how would you modify the statements on page 

 1 1 relative to the ploidy of gametes? 



11.5. Describe at least two different ways that the trisomy causing Down's syndrome 



may originate. 



1 1.6. The only presently known case of trisomy for a chromosome of the 19-20 group 

 occurred mosaically in a six-year-old boy. To what do you attribute this? 



