320 



( IIM'TI K 24 



l isi 01 Chromosomai Markers of E. coli — continued 



Ke\ to genetic symbols 



Activity affected 



metF 



metE 

 mtl 



III IIC 



O 

 pan 



pheA.B 

 pho 



P il 



pro A 



proB 



proC 



purA 



purB 



purC.E 



purD 

 pyrA 

 pyrB 

 pyrC 



pyrD 

 pyrE 

 pyrF 



Rarg 



Rgal 



Rl pho, R2 pho 



R try 



RC 



rha 



serA 



serB 



sir 



sue 



T1J5 rec 



Tl rec 



T6, colK rec 



T4 rec 



thi 



tin 



thy 



tryA 



iryB 



tryC 



tryE 



tryD 



tyr 



uvrA 



xyl 



methionine 



methionine or cobalamin 



mannitol 



mucoid 

 O antigen 

 pantothenic acid 

 phenylalanine 



phosphatase 



pili i fimbriae) 



proline 



proline 



proline 



purine 



purine 



purine 



purine 



uracil + arginine 



uracil 



uracil 



uracil 



uracil 



uracil 



repressor 



repressor 



repressor 



repressor 



RNA control 



rhamnose 



serine 



serine 



streptomycin 



succinic acid 



phage receptor site 



phage receptor site 



phage and colicine receptor site 



phage receptor site 



thiamine 



threonine 



thymine 



tryptophan 



tryptophan 



tryptophan 



tryptophan 



tryptophan 



tyrosine 



ultraviolet radiation 



xylose 



prohahly 5,10-mcthylene tetrahydrofolate reductase 



unknown 



probably mannitol dehydrogenase 



regulation of capsular polysaccharide synthesis 



somatic antigen 



alkaline phosphatase 



supports syntrophic growth of proA mutants 



supports syntrophic growth of proA mutants 



adenylosuccinic synthetase 



adenylosuccinase 



5-aminoimidazole ribotide(AIR ) to 5-aminoimidazole 



4-(N-succinocarboxamide) ribotide 



biosynthesis of AIR 



carbamate kinase 



aspartate transcarbamylase 



dihydroorotase 



dihydroorotic acid dehydrogenase 



orotidylic acid pyrophosphorylase 



orotidylic acid decarboxylase 



arginine repressor 



galactose repressor 



alkaline phosphatase repressor 



tryptophan repressor 



regulation of RNA synthesis 



utilization of D-rhamnose 



3-phosphoglycerate dehydrogenase 



phosphoserine phosphatase 



resistance, sensitivity, or dependence on streptomycin 



resistance to phages Tl and T5 

 resistance to phage Tl 

 resistance to phage T6 and colicine K 

 resistance to phage T4 



thymidylate synthetase 



tryptophan synthetase, A protein 



tryptophan synthetase, B protein 



indole 3-glycerolphosphate synthetase 



anthranilic acid to anthranilic deoxyribulotidc 



3-enolpyruvylshikimate 5-phosphate to anthranilic acid 



reactivation of UV-induced lesions in DNA 

 utilization of D-xylose 



* Established systems of genetic nomenclature are retained wherever possible, except that capital letters be- 

 ginning with the letter A are arbitrarily assigned to functionally related gene loci which do not conform to 

 the system of bacterial genetic nomenclature proposed by M. Demerec (1963). 



t Denotes enzymes controlled by the homologous gene loci of Salmonella typhimurium. 



