Genetic Amino Acid Coding 



447 



Speakers {I. to r.) M. W. Nirenberg, F. Lipmann, and S. Ochoa at a sym- 

 posium on the RNA code held January, 1962, at Indiana University. 



Weisblum, B., Gonano. F., von Ehrenstein. G.. and Benzer, S.. "A Demonstration of 



Coding Degeneracy in the Synthesis of Protein," Proc. Nat. Acad. Sci., U.S., 



53:328-334, 1965.' 

 Woese, C. R., Hinegardner, R. T., and Engelberg, J., "Universality in the Genetic 



Code," Science, 144:1030-1031, 1964. 

 Yanofsky, C, Carlton, B. C, Guest, J. R., Helinski, D. R., and Henning, U., "On the 



Colinearity of Gene Structure and Protein Structure," Proc. Nat. Acad. Sci., U.S., 



51:266-272, 1964. 

 See Supplement X. Other references can be found at the end of Dr. Crick's Nobel 



Prize Lecture. 



QUESTIONS FOR DISCUSSION 



34.1. Do you expect the genetic code for amino acids to be the same in all free- 

 living organisms? Explain. 



34.2. Compare the replication of an RNA virus with the replication of a polypeptide 

 chain. 



34.3. Prepare a report on advances in our understanding of the genetic code since 

 the present account was written (November 1964). 



34.4. What evidence can you present that the attachment of messenger RNA to the 

 ribosome does not involve extensive complementary base pairing? 



34.5. Give evidences that messenger RNA is single-stranded. 



