404 CHAPTER 36 



QUESTIONS FOR DISCUSSION 



36.1. What evidence can you cite thai one strip oi messenger RNA can he long 

 enough to contain several structural genes of an operon? 



36.2. In what respects are the alleles o . . and o c similar? In what respects arc 

 the) different? 



36.3. How does an operator gene differ from a regulator gene? 



36.4. Do you suppose that the nucleotide sequence is longer in an operator gene than 

 in other genie members of an operon? Why? 



36.5. Does prophage behave as though it contains one or more regulator genes? 

 Does prophage behave as a repressed operon? Explain. 



36.6. Some workers classify genes into three types: those for structure; those for 

 regulation: and those for operation. Do you believe this distinction is basic? 

 Do you believe it is useful? Explain. 



36.7. What specific kinds of phenotypic effects may operons produce in man? 



36.8. In what ways do genes function? 



36.9. What is your present concept of the "gene"? 



36.10. Discuss the view that in E. coli, rll deletion 1589 involves an operon. 



36. 1 1 . What conclusions could you draw from the report that with respect to the 

 bacterial linkage map certain operons are arranged clockwise and others counter- 

 clockwise? 



36.12. What support can you give to the hypothesis that o° mutants involve nucleotide 

 deletions? 



36.13. Apply the operon concept to hemoglobin production in man. 



36.14. Are all regulator genes suppressor genes? Explain. 



