Regulation of Gene Action — Gene Control Systems in Maize 



471 



SUMMARY AND CONCLUSIONS 



A large number of cases involving the control of gene action in maize are known. 

 Those analyzed prove to comprise several regulator gene-operator gene systems com- 

 parable to those found in bacteria. In maize both genes of this two-element control 

 system are transposable to new loci. Paramutation probably involves a gene control 

 system. Other, more complicated, control systems (superregulatory. for example) also 

 exist. 



Royal Alexander Brink, in 1961. 



REFERENCES 



Brink, R. A.. '"Very Light Variegated Pericarp in Maize," Genetics, 39:724-740, 1954. 



Brink, R. A., "Paramutation and Chromosome Organization," Quart. Rev. Biol., 35: 

 120-137, 1960. 



Brink, R. A.. Kermickle. J. L.. and Brown, D. F., "Tests for a Gene-Dependent Cyto- 

 plasmic Particle Associated with R Paramutation in Maize," Proc. Nat. Acad. 

 Sci., U.S., 51:1067-1074, 1964. 



McClintock, B., "Some Parallels between Gene Control Systems in Maize and Bacteria," 

 Amer. Nat., 95:265-277, 1961. 



McClintock, B., "Topographical Relations between Elements of Control Systems in 

 Maize," Carnegie Inst. Wash. Yearb., 61 ( 1961-1962) :448-461, 1962. 



McClintock, B., "Further Studies of Gene-Control Systems in Maize," Carnegie Inst. 

 Wash. Yearb., 62 ( 1962-1963) : 486-493, 1963. 



van Schaik, N. W., and Brink. R. A., "Transpositions of Modulator, A Modifier of 

 the Variegated Pericarp Allele in Maize," Genetics, 44:725-738, 1959. 



