

IM)I \ 



deoxycytidine, 257, 258 

 deoxycytidylic acid, 259 

 deoxyguanosine, 257, 258 

 deoxyguanj tic acid, 259 

 DNase (deoxyribonuclease), 261. 



281 282, 285 

 n\ \ (deoxyribonucleic acid), 



253 

 amino acids in, 276. 45? 

 backbone, 280, 271. 276. 397 

 oi Bacillus, 287 

 base composition. 266. 452- 



453 

 biological replication. 288-289 

 breakage and exchange. 299. 



300 

 5-bromo uracil in. 452 

 call thymus, 2S6 

 in cell membrane. 506 

 in chloroplasts. 372 

 coiling. 268 



conserved or not. 423. 492-494 

 copohmers. 287-288. 301. 399, 



44') 

 containing ribotides, 289 

 content of col factors, 360 

 content of F. 323 

 crab. 288 

 denaturation and renaturation, 



275. 301-302. 496-497 

 </(• novo synthesis. 287-288 

 dinncleotide sequences, 285— 



288 

 double helix. 267 

 enzymatic degradation. 281, 



2S2 

 en/vmes for precursors. 450, 



451 

 evolution of. 511-514 

 as genetic material, 261-262, 



296. 340 

 per genome. 265, 287, 323, 



360 

 glucose in. 450, 452 

 with heavy nitrogen. 272-274 

 H -bonding in. 269, 284 

 homologous. 298 

 homopolymers. 287-288, 301 

 major and minor grooves. 269, 



426 

 melting. 275. 301. 496-497 

 as messenger. 494 

 methylation of, 429 

 in mitochondria, 377, 378 

 molecular weight, 301. 348 

 of Mycobacterium, 286 

 native. 275 

 nucleoside and nucleotide 



ends. 280 281 

 organization in vivo, 265-271, 



275-276 

 parallel synthesis. 453 



penetration. 297 



polymerases, 2x0. 288. 450, 



451 

 and polynemy, 275 

 primary structure. 259-260. 



265 ' 

 as primer-template. 271. 283- 



285, 509 

 quantity measured. 260-261 

 replication and strand separa- 

 tion. 272 

 replication /'/; vitro, 279-289 

 replication ;'// vivo, 271-274, 



484 

 reversible synthesis, 285 

 satellite. 323 

 scission, 302 

 secondary structure, 266. 267- 



271. 267 

 strand growth. 281, 282, 286, 



453 

 strand recombination. 271-275 

 swivel in replicating. 453 

 and synapsis. 298 

 synthesis, extended and lim- 

 ited, 281-283 

 regulation, 449-453 

 from RNA, 289, 455 

 terminology, 262 

 and transduction, 331 

 and transformation. 296, 396 

 ultraviolet absorption, 275 

 uracil in. 452 

 Watson-Crick model. 267 

 X ray diffraction pattern, 267, 

 268 

 deoxyribonucleoprotein, 253 

 deoxyribosidase (reductase), 449 

 deoxyriboside. 257, 258 

 deoxyribotide, 257, 258, 259 

 depurination. 396 

 derepression, 458 

 detecting chromosomal changes, 



174-175 

 detrimental equivalents, 218 

 development, and gene action, 

 79-85. 501-506 

 human. 107-110. 417. 486 

 diabetes. 4, 220 

 diakinesis, 17, 18. 20 

 Didinium. 454. 513 

 differentiation and gene action. 



501-506 

 diffuse (growth) stage, 18 

 dihybrid. 45 



dimers. in hemoglobin. 412 

 tin mine. 396, 397 

 uracil. 397 

 Diplococcus (see Pneumococcus) 

 diploid. 1 I 



diplonema. 16. 17, 18. 19 

 discrete variables, 520, 521-534 



disomic, 156 



Dissociation, 384 386, 386, 400 



dogs. 55 



dominance. 35, 49. 195. 202, 242 



donors, intermediate, 357 



dosage compensation. 484-489 



"double cross" breeding. 211,212 



double recessive. 45 



doublets, shared. 443, 444 



doubling dose. 223 



Down's syndrome (mongolism), 



158-160. 160, 172 

 drift, random genetic. 203, 219. 



242 

 Drosophila, bibliographies, 29 

 chromosomes in nature, 236, 



237, 238 

 dosage compensation, 487-489 

 and extranuclear genes, 369- 



370 

 eye anlage, 422 

 larval salivary gland, 253 

 melanogaster, 23, 24, 480 

 chromosome. 95 

 chromosome map. 185 

 crossover map of X, 132 

 monosomic and trisomic, 



156 

 mutant detection in, 195— 



198 

 salivary gland chromosomes, 



153, 154, 155 

 sex determination, 102-107 

 and sex-linkage. 90-98 

 triploid. 152 

 persimilis, 245-246 

 position effects, 473-481 

 pseudoobscura, 209. 216, 217, 

 242. 243, 245-246. 488-489 

 segregation distortion in, 386- 



388 

 wing. 50, 60, 480 

 duplication. 170, 474, 477 

 dwarfism. 79. 83, 204 

 dyad, 16 



earthworm. 1 1 1 



ecdysone and puffing, 492 



Hchinus (sea urchin). 152 



eclipse period. 340. 341, 501 



ecological barriers, 244 



egg, 5, 24, 25, 26 



electrons, fast, and mutation. 182, 



183 

 embryo. 25, 26 

 embryology, 79-81, 81, 417, 486, 



502 

 encephalitis, 363 

 endolysin, 342 



endoplasmic reticulum. 7, 504 

 endoreplication. 153-155 

 endosperm, 25, 26, 384, 487 



