288 EXPERIMENT STATION" RECOED. 



coitus (2 per cent solution of lysoform recommended). Treat heifers till cured 

 according to veterinary advice, suspending the treatment during oestrum. 

 Douche with 2 per cent solution of carbonate of soda during oestrum, especially 

 immediately before covering. After the seventh month of pregnancy use only 

 the mildest of medicaments, such as ointments containing a very little bella- 

 donna and only 0.5 per cent of a nonirritant antiseptic, lysoform, etc. Isolate 

 or slaughter cows suffering from chronic metritis and those in whom oestrum 

 has entirely ceased. After parturition inject weak solutions of iodiu — a tea- 

 spoonful in each quart of tepid water." 



The treatment of contagious vaginitis in cattle, E. Waltee and A. Gaetnee 

 (Berlin. Tierdrztl. 'Wchnschr., 28 (1912), JSi'o. 8, pp. ISS-UO ; abs. m Jour. Corn- 

 par. Path, and Ther., 25 {1912), No. 1, pp. 1.'i-82). — In attempting to discover 

 a disinfectant which might be kept in constant contact with the mucous mem- 

 brane and one which is at the same time simple of application, the authors 

 Lave made successful use of a eucerin salve. In preparing this ointment the 

 anhydrie eucerin is gradually worked up in a mortar with the desired quantity 

 of a watery solution of the medicament until the mixture is quite uniform. 

 The complete absorption of the water is indicated by the clinging of the mix- 

 ture to the sides of the mortar. 



In the experiments here reported eucerin ointments containing 10 per cent 

 bacillol, 0.5 per cent sublamin, and 25 per cent water; 10 per cent sapoformol, 

 0.5 per cent sublamin, and 25 per cent water; 8 per cent bacillol, 0.6 per cent 

 sublamin, and 25 per cent water ; 3.5 per cent copper sulphate and 25 per cent 

 water ; 10 per cent copper sulphate and 25 per cent water ; 10 per cent copper 

 citrate and 25 per cent water ; 8 per cent bacillol, 0.6 per cent sublamin, and 

 25 per cent water ; 8 per cent bacillol, 0.5 per cent sublamin, and 25 per cent 

 water; and 8 per cent bacillol and 25 per cent water, respectively, were em- 

 ployed. 



From the results obtained it may be concluded that animals affected with 

 vaginitis can be cured in this way. " The results are the same whether the 

 cases are recent or of long standing, and also if other methods of treatment 

 ha-\e been tried. This result is obtained by the application of a disinfectant 

 which is present in the same proportion in a number of other materials that 

 are in common use for the treatment of this disease. Since these preparations 

 are by no means so successful, the authors concluded that the difference must 

 lie in the vehicle in which the disinfectant was suspended. . . . 



" It is absolutely necessary that the eucerin mixture be applied to the whole 

 of the diseased membrane. . . . Relapses ceased to occur when the salve was 

 distributed throughout the vagina by means of a special instrument — cunn- 

 fricator. The even and thorough distribution of the salve over the mucous 

 membrane by means of this instrument was controlled by the examination 

 of 3 animals that were slaughtered. Ten gm. of the mixture were smeared 

 over the walls of the vagina by its means shortly before death, and after 

 slaughter it was found that the entire mucous membrane was covered with a 

 layer about 1 mm. thick. In practically all the experimental animals applica- 

 tion of the bacillol mixture caused the disappearance of the nodules within 

 4 to 5 days, and it was only in quite exceptional cases that traces of the lesions 

 were visible on the fifth day. In cases where the treatment was continued 

 for longer periods it was done with the idea of preventing relapses with greater 

 certainty and not to improve the local curative effect. The treatment was 

 quite simple and was not followed by any untoward symptoms, such as rest- 

 lessness and straining. The nature of the treatment with the soft, semifluid 

 salve is such that animals in the last stages of pregnancy may be submitted 

 to it without hesitation. . . . 



