882 EXPERIMENT STATION RECORD. 



The experiments led to the following conclusions : " The alkaloidal prepara- 

 tion from Z. iniermedius slows the heart rate by acting apparently on the cardio- 

 inhibitory center. It slows respiration by an effect involving the respiratory 

 center. It causes vaso-dilation. In quantities approachng the fatal dose it 

 hastens the heart rate and produces both irregularity of the heart beat and 

 convulsive respiration. The fatal dose given intravenously to dogs stops the 

 heart before respiration ceases. The fatal dose for guinea pigs is between 

 4.6 and 5.1 mg. per 100 gm. of animal. It has a very powerful action, whether 

 injected or fed, both as a purgative and an emetic." 



In order to ascertain the pharmacological properties of the resin present a 

 series of experiments was conducted, the results of which demonstrated it to 

 be physiologically inert. 



The effect of Tilletia in the food of domestic animals, G. Pusch (Ztschr. 

 Infektionskrank. u. Ilijg. Haiisticre, 11 {1912). No. 1, pp. l-l'i). — The investi- 

 gations here reported have led the author to conclude that domestic animals 

 may consume large quantities of wheat smut spores for a long period without 

 ill effect ; and that gestating ruminants and swine may consume large amounts 

 of smutty wheat without aborting. 



A mycotic enzootic caused by blighted barley, C. Dabmagnac (.4 6s. in 

 Yet. Jour., 68 {1912), No. JiJi5, pp. JfS't, JfSo). — A brief report of forage poison- 

 ing in 21 horses caused by feeding on barley injured by smut {Ustilago carho). 



Destruction of bacteria by leucocytes, S. Suzuki {Arch. Hyg., 15 {1912), 

 No. 4-5, pp. 224-23Jf). — A systematic quantitative study of cytolytic activity of 

 leucocytes toward various micro-organisms was made. It was noted that with 

 the fairly sensitive micro-organisms, leucocytes in doses of 0.025 gm. are strongly 

 bactericidal. In the case of the less sensitive micro-organisms, e. g., typhoid, 

 cholera, and fowl cholera, the cytolytic activity ceases v/ith the minimum doses, 

 and even with quantities of 0.5 gm. this activity is very weak, and amounts of 

 from 0.1 to 0.15 are necessary. Leucocytes in 0.025 gm. doses were more effec- 

 tive against the hog erysipelas bacterium than larger doses. 



The development of a leucocytozoou of guinea pigs, E. H. Ross {Ann. 

 Trop. Med. and Par., 6 {1912), No. 1, pp. 69-16, pi. i).— " Kurloff's bodies are 

 parasites, lymphocytozoa inhabiting only the mononuclear cells of the guinea 

 pig's blood. These lymphocytozoa have an intracorpuscular stage, and ulti- 

 mately give rise to free-swimming, spirochete-like bodies, which may be gametes. 

 The development of the spirochete-like body is demonstrated. The name Lym- 

 phocytosoon cohaya; is suggested for this parasite." 



The new mycoses, De Beurmann and Gougerot {Les NouvelJes Mycoses. 

 Paris, 1912, pp. 165, figs. 16). — This work deals with the exascoses (ex-blasto- 

 mycoses), oidiomycoses, sporotrichoses, botrytimycosis, oosporoses, and hemi- 

 sporosis. 



Immunity facts and the outlook, H. Much (Wiirisb. Ahhandl. Gesam. Geb. 

 Prakt. Med., 9 {1909), No. 6-1, pp. 111-184). — This is a comprehensive digest 

 of the facts relating to immunity. It deals particularly with the present knowl- 

 edge of the subject as applied to both human and veterinary medicine. 



In regard to opsonins, A. Frenzel ( Uehcr Opsanine. Inaug. Diss., Univ. 

 Lelpsic, 1911, pp. 81). — The Wright method for determining the opsonic index 

 was found to be satisfactory and the percentage of errors was never greater 

 than 10 per cent. The opsonic index of normal individuals, man and animals, 

 was found to vary between 0.9 and 1.1. The indexes of infected individuals, 

 which included tubercular humans and bovines, and humans with staphylo- 

 coccic infections, were found to be in from 40 to 50 per cent of the cases within 

 the normal figure, while all the rest had subnormal or hypernormal indexes. 

 The behavior of blood sera of sound horses and other domesticated animals 



