VETERINARY MEDICINE. 487 



The author concliules that " pyemic arthritis may arise from either a pyemic 

 or septic infection; that one or both may be present at the same time in the 

 same snbjec.t ; that the septic form assumes a more acute type, and usually 

 terminates fatally within a few clays; that the pyemic infection will yield 

 readily to potent cocci antitoxin, and we believe will bo much assisted in a 

 more rapid convalescence by conjunction with nuclein, especially in weakly 

 foals; that large doses of serum should be employed early and discontinued as 

 soon as resolution is established." 



The history of glanders in the French army, L. Magnin (Rev. G6n. Med. 

 V^t., 12 {IDOS), 1^0. J39-]J,0, pp. 396-.'i 12). —This history is based on statistics 

 from the commission on equine hygiene and the reports of the veterinary chiefs 

 of the service. 



Dourine (Dcpt. Agr. Oiluica, Health Aiiini. Branch, Spec. Rpt. Dourinc, 1901, 

 pp. 63, pis. IS, charts 3). — A short historical review of the occurrence of this dis- 

 ease in Canada, where it has for several years existed to a limited degree among 

 horses in certain districts in southern Alberta and in one locality in southwest- 

 ern Saskatchewan, is presented by J. G. Rutherford (pp. 3-6) and the clinical 

 and pathological features of the disease as occurring in cases studied are re- 

 ported by C. H. Higgins (pp. 7-31). The first demonstration on the North Ameri- 

 can continent of the presence of Trypanosoma eqitiperdum in naturally infected 

 cases of dourine is said to have been that of Watson and Gallivan, which is here 

 reported. With this discovery it was definitely determined that the disease is 

 identical with the dourine of other countries. 



The demonstration of this parasite is largely a matter of obtaining suitable 

 cases coupled with systematic experiments and close observation. The possi- 

 bility of diagnosing the disease by purely clinical means is considered as fully 

 established. As with sleeping sickness, it is believed that the lesions produced in 

 cases of dourine are due to a lai-ge extent to the toxin present. " Certain bodies 

 have been observed in some of the preparations taken by Watson, and later 

 studied by both of us, which may be trypanosomata in an involution stage. I 

 can not agree with Thiroux and Teppaz, however, that the red granules seen in 

 the large mononuclear lymphocytes of horses (when stained with eosin and 

 methylene blue in any of its combinations), represent the remains of trypanoso- 

 mata, for we have observed these granules almost without exception in smears 

 taken from the general and peripheral circulation of healthy horses." 



The pathological anatomy and blood examinations of the cases studied are 

 reported in detail. E. A. Watson reports a case of dourine with experimental in- 

 oculations and miscellaneous notes on the symptomatology and diagnosis (pp. 

 32-51) . In Appendix A several cases of natural dourine are reported (pp. 52-^4) . 

 In Appendix B, a brief report made by E. T. Davison to the Bureau of Animal 

 Industry of this Department, concerning an investigation of the disease at Leth- 

 bridge. Alberta, is given (p. 55). Appendix C contains an article on the identity 

 of dourine by Schneider and Buffard (pp. 56, 57), previously noted (E. S. R., 

 17, p. 809). 



Trypanosomiasis of horses at Tonquin, Hallot (Rev. Gen. M^d. Yet., 12, 

 (1908), Xo. 13.5-13G, pp. 129-1.)!, figs. C).— The author here reports a series of 

 enzootics which he has studied in Tonquin, French Indo-China. In horses the 

 disease terminates in death, while with cattle it is nearly always benign. The 

 author has experimentally infected the guinea pig, rat, dog, and calves with 

 the equine virus. In transmission experiments tabanids conveyed the disease 

 from an infected to a healthy guinea pig. Experiments with Stomoxys resulted 

 negatively. 



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