488 EXPERIMENT STATION RECORD. 



The treatment of trypanosomiases in horses by orpiment alone or in con- 

 nection with atoxyl, A. Thiroux aud L. Teppaz {Ann. Inst. Pasteur, 23 {1909), 

 No. 3, pp. 2J/0-252; ahs. in Jour. Compur. Path, and Ther., 22 (1909), No. 2. 

 pp. J62-Um). — Previously noted from another source (E. S. R., 21, p. 184). 



Leucocytozoon piroplasmoides of epizootic lymphangitis of the horse, A. 

 Thiroux and A. Teppaz {Coiupt. Rend. Acad. Scl. [Paris], UfJ (IDOS), No. 22, 

 pp. 1075. 1016). — The aaithors briefly review the literature on the etiology of 

 this disease, aud report studies in a horse that had been treated for and cured 

 of trypanosomiasis by the use of orpiment and atoxyl. They found the mor- 

 l)hology and i)arasitic habits of the protozoa present in the sores to be much 

 similar to those of Hclcosoma tropicum. and regard the disease as the equine 

 variety of tbe oriental sore in man. 



The treatment of dog distemper by means of vaccination, R. Bissauge 

 and L. Naudin [Rev. Gen. Med. Vet., 12 {1908), No. IJ/l, pp. 503-507 ) .—During 

 the course of their practice the authors have experimented on numerous sub- 

 jects with the various therapeutic agents. They conclude that none of these 

 has any prophylactic value. The Swiss yeast of Pury has given successful 

 results in many cases, particularly with dogs in which the nervous symptom 

 arose at the beginning. The antistreptococcic serum of the Pasteur Institute 

 and that of Dassonville and Wissocq have given equally encouraging results. 

 In their practice the authors have given preference to the latter serum, which 

 they now use in a systematic way. In order to utilize the therapeutic power of 

 this serum and obtain the best results from its use applications must be made 

 at the onset of the disease, before lesions have formed. 



The successful drug treatment of canine piroplasmosis, together with 

 observations upon the effect of drugs on Piroplasma canis, G. H. F. >suttall 

 and S. Hadwen (Parasitology, 2 {1909), No. 1-2, pp. 156-191, fig. /).— The 

 authors' conclusions follow : 



" We have discovered that trypanblau and trypaurot are highly eflicient 

 remedies in the treatment of canine piroplasmosis, no drug or mode of treatment 

 having hitherto been found to exert any appreciable effect upon this very fatal 

 disease. The drugs exert a direct and observable effect upon the parasites {a.) 

 by causing the pyriform parasites to quickly disappear, aud (b) in most cases, 

 by causing the total disappearance of the parasites from microscopic observation 

 in the peripheral blood. The disappearance of the parasites from the blood is 

 usually temporary, the parasites reappearing in small numbers after an interval 

 of 9 to 12 days, but the dogs, as a rule, show no symptoms and gradually 

 progi'ess toward recovery. In our experience there is but slight loss of weight 

 in treated animals, this being in marked contrast to what is usually observed 

 in dogs which recover naturally. In the 2 dogs which died of a relapse the 

 parasites reappeared after an interval of 4 to 5 days. . . . Arsacetin and 

 soamin exert no curative effect upon canine piroplasmosis." 



On the supposed development of Trypanosoma lewisi in lice and fleas, and 

 the occurrence of Crithidia ctenophthalmi in fleas, C. Strickland ( Parasitol- 

 ogy, 2 {1909), Nos. 1-2, pp. 81-90).— The alimentary tracts of 104 lice {Hcema- 

 topinus spinulosus) , which had been taken from rats infected with 'f. lewisi, were 

 examined. In 51 lice no trace of T. lewisi could be found, but in 53 lice T. leicisi, 

 unchanged in every particular, was found in various parts of the gut. The 

 trypanosome was seen to be quite unchanged in stained preparations. 



The alimentary tracts of 45 fleas (ctenophthalmus agyrtes) which had fed on 

 infected rats were also examined, but in 43 fleas T. lewisi could not be found. 

 They disappeared very rapidly from the ingested blood and could not be found in 

 stained preparations. In 2 fleas trypanosomes were found, but they did not differ 



