584 EXPERIMENT STATION RECORD. 



to accept the view that the virus of the disease may, enter the system through 

 the digestive tract, aud considers it necessary to examine carefully the forage 

 and grain used for feeding and to give particular attention to the quality of the 

 drinking water. 



Equine anemia, W. B. Mack (Nevada Sta. Bui. 68, pp. 7-96, pi. 1, charts 

 ^3). — This is a detailed report of preliminary investigations of a disease among 

 horses which exists in eastern Nevada and is probably identical with infectious 

 anemia of Europe. It is believed that it may also prove to be identical with 

 the swamp fever of Manitoba and the Middle Western States. 



" The disease is characterized clinically by profound cardiac and respiratory 

 disturbances, an irregularly remittent fever, rapid emaciation, marlced loss of 

 nervous and muscular energy, progressive anemia, edema, and, in the last 

 stages, by capillary hemorrhages. 



" The primary lesion appears to consist of a progressive destruction of the 

 red blood corpuscles, followed secondarily by parenchymatous degeneration of 

 the kidneys and liver, and sometimes of the cardiac muscle; and by extensive 

 changes in the vascular system. Toward the end of the course of the disease 

 extensive capillary hemorrhages occur, especially in the heart, the gastro- 

 intestinal tract, and the kidneys, and usually in the other visceral organs, 

 beneath the serous coats, and into the subcutaneous aud intermuscular con- 

 nective tissues. The spleen is engorged and sometimes degenerated. The bone 

 marrow undergoes profound alteration. 



" The symptoms and lesions encountered appear sufficient to constitute a dis- 

 tinct clinical and pathological entity. 



" Experiments apparently indicate the infectious character of the disease ; 

 that the virus exists in the blopd; that the infectious agent is not revealed by 

 the usual methods employed to demonstrate the presence of bacteria or pro- 

 tozoa ; and that the disease is not contagious by the ordinary contact of 

 animals. 



" The natural mode of dissemination yet awaits demonstration. 



" The mortality exceeds 90 per cent with recovery more apparent than real. 



" Treatment has not been successful to any extent." 



.A bibliography is appended. 



Glanders, W. B. Mack (Nevada Sta. Circ. 1, pp. 8). — A popular account of 

 glanders, including information concerning its prevention and eradication, 

 intended to furnish information to ranchmen and horse owners in certain 

 localities in Nevada, where the disease has been discovered. 



The antistreptococcic value of mallein, Busy (Rcc. Med. Yet., 85 (1908), 

 No. 19, pp. 617-622). — During the course of an epizootic of strangles in horses 

 suspected of having glanders the author obtained good results from the use of 

 mallein. 



Contribution to the study of epizootic lymphangitis of horses in Senegal, 

 A. Thiroux and L. Teppaz (Ann. Inst. Pasteur, 23 (1909), No. 5, pp. Ji20-1{25, 

 fig. 1). — In addition to the information previously noted (E. S. R., 21, p. 488), 

 the authors here consider the culture of the parasite, inoculation experiments, 

 and method of treatment. 



Experiments in which transmission of the disease was attempted by trans- 

 ferring pus to wounds resulted negatively. The disease appears to be localized 

 in certain colonies on the Mediterranean coast where malaria occurs. It 

 sometimes appears in France along canals and rivers in horses employed in 

 towing boats. With this evidence in view the authors consider it very prob- 

 able that the disease is transmitted by blood-sucking flies and possibly by 

 mosquitoes. 



