VETERINARY MEDICINE. 787 



(1909), No. 1099, p. 89).— The iuitlior considers the so-called failures of the 

 tuberculin test, namely, failure to reveal an existing tuberculosis, and an indica- 

 tion of the disease when at the post-mortem examination evidence is lacking. 



With rabbits and jiuinea pigs, in ft)ur-fiftlis of the cases In which inoculation 

 with attenuated bacilli Is i)racticed the resulting lesions are not only micro- 

 scopic but also atypical. Intraperitoneal inoculation alone of these bacilli in 

 rabbits and guinea pigs produces typical tubercles of millet seed size in the 

 epiploon and the perigastric lymphatic glands. 



In young goats and young cattle the subcutaneous injection of attenuated 

 bacilli is followed by a temporary swelling of the corresponding lymphatic 

 glands, but when these glands have regained their normal volume it is generally 

 impossible to find histological lesions in them. When the attenuated bacilli 

 are injected intravenously, histological sections may show some slight lesions. 

 Notwithstanding the absence of macroscopical lesions and the extremejy dis- 

 crete character of the histological alterations, young cattle which have received 

 modified tubercle bacilli always present at a given moment the physiological 

 reaction of tuberculous infection. 



These observations demonstrate that there is no necessary relation between 

 the sensibility of the subject to the tuberculin or the sero-agglutination test and 

 the presence of a macroscopic tuberculous lesion. A positive reaction to tuber- 

 culin nearly always indicates that the subject has been infected by tubercle 

 bacilli, but does not necessarily indicate the existence of macroscopic lesions, 

 and does not assist in the prognosis of the case. It is im])ossible to say whether 

 the lesions present in a reacting animal will retrogress or develop into a 

 clinically evident tuberculosis. The owner desiring to stamp out tuberculosis 

 in his herd should, in practice, regard every reactor as infected. 



Tuberculosis infection and immunization against tuberculosis by the 

 dig'estive tract, A. Calmette (Rev. 8ci. [Paris], 5. set:, 10 (1908), No. 18, pp. 

 r45-551; ahs. in Rev. V6t. [Toulouse], S.'i (1909), No. 2, pp. 113-117).— Au 

 account w^hich was presented before the Harvey Society of New York, October, 

 lOOS. 



Experiments with von Behring's bovovaccine. I, Tests with cattle not 

 protected against natural tuberculosis infection, G. Regneb and O. Sten- 

 STROM (MedilcL E. Lnndtbr. Sti/r. [Stcctlcn]. VM)8, No. 11 {l.'iO), pp. i,0+ 

 ril; Centbl. Bali, [etc.], 1. Aht., Orig., J,8 (1909), No. .5, pp. 628-657).— The 

 authors conclude from experiments in 10 different Swedish herds that bovovac- 

 cine is an easily applied method of inoculation which is, moreover, entirely 

 harmless, in so far as can be judged after four years' practical experience with 

 it. While it exercises a beneficial effect in certain cases, it can not be recom- 

 mended as an effective means of combating bovine tuberculosis without accom- 

 panying hygienic precautions, like isolation, sterilization of milk fed to calves, etc. 



Some facts about tuberculous cattle, E. C. Sciiroeder (U. S. Dept. Affi: 

 Yearbook 1908, pp. 217-226, pis. -J). — Data regarding tuberculosis and its trans- 

 mission are briefly considered. The author concludes that " for the protection 

 of public health it seems imperatively necessary that regulations should be 

 made requiring either that all milk must be obtained from cows certainly free 

 from tuberculosis, stabled, milked, i)astured, et?., in an environment free from 

 tuberculous infection, or that it must be sterilized or pasteurized before it is 

 used as a beverage or in the manufacture of butter and other dairy products." 



The tuberculosis situation, M. H. Reynolds (Breeder's Gaz., 65 (1909), No. 

 25, pp. 1J,02. l-'i03).—''l think it fair to say that the Bang method on private 

 farms has not been demonstrated as generally practicable in this country ex- 

 cept in the case of very valuable herds. . . . Apparently the one great thing 

 15149— No. S— 09 7 



