VETERTNAJIY MEDTCTNE. 281 



'if the first year. The resistance of inoculated cattle toward natural infection 

 from other tuberculous cattle is never striking? and disappears after a few 

 mouths. 



In further experiments to test von Behring's method 2 intravenous vaccina- 

 tions were given in the place of the one previously recommended. It was 

 found that the resisting power of cattle thus treated was at first very pro- 

 nounced or almost absolute, but tliat it was not of long duration, disappearing 

 entirely within IS months. The author concludes from his experiments that 

 at present the only method for controlling tuberculosis which has stood prac- 

 tical test is that of Bang. 



An unusual form of tuberculosis in hogs, J. Bohm (Ztschr. Fleisch ii. Milch- 

 liiiil.. 1"! (191)7). Xo. .'', p. 311). — In the examination of a case of advanced 

 tuberculosis in a hog it was found that tubercles were present not only in the 

 orgaiw usuallj' affected, but also in the fat tissue. The tubercles in the fat 

 tissue showed no anatomical connection with muscle fibers or with lymph or 

 blood vessels. 



Tuberculosis in the region of certain canals near Modena, R. V. Rossi 

 (Clin. Vet. [Milan]. 30 (liiol). No. 1. pp. 2-1). — A study was made of tuber- 

 < ulous cats and rats in the region of certain canals which were contaminated 

 to some extent with tubercle bacilli. The author comes to the conclusion that 

 tiuid contaminations which enter the canal may have contributed to the in- 

 creased percentage of tuberculosis among these animals, but that the refuse meat 

 material transported in the canals is the chief source of the disease. 



Distribution of tuberculin and mallein by the Bureau of Animal Industry, 

 M. Dorset (V. S. Dcpt. Af/r. Yearbook 1906. pp. 3Jtl-3i.'i). — Attention is called 

 to the great importance of means for the diagnosis of infectious diseases iu 

 advance 'of the development of clinical symptoms. A brief historical state- 

 ment is given of the use of tuberculin and mallein in detecting tuberculosis and 

 glanders. The Bureau of Animal Industry furnishes tuberculin and mallein to 

 Federal, t^tate, county, or city officials under an agreement that the latter fur- 

 nish records of the tests and of autopsies upon all animals which are slaugh- 

 tered. During the fiscal year 1905-G 103,000 doses of tuberculin and 10,000 

 doses of mallein were distributed. 



Observations on the mallein test, W. Jowett (Yet. Rec, 19 {1901), A'o. 983, 

 PI). 125-129). — Considerable difference of opinion has prevailed regarding the 

 length of time which should be allowed to elapse after one mallein injection 

 b(>fore another one is given in cases of doubtful reaction. This matter has been 

 larefully studied by the author, with the result that the interval between 2 

 mallein injections apparently need not be longer than a few days or merely long 

 enough to allow the animal to return to a normal temperature. In a study of 

 mallein reactions the thermic reaction appears to be more delicate and reliable 

 than the local reaction at the point of injection. 



Experimental glanders in guinea pigs, M. Nicolle (Ann. Inst. Pasteur, 21 

 (lUdl). \o. //. lip. 2Sl-29'i). — A series of inoculation experiments was carried 

 on in testing the reaction of guinea pigs to glanders virus obtained from differ- 

 ent sources and subjected to different conditions of environment. When intra- 

 cardiac injections of glanders virus were made, the external symi)toms of the 

 disease appeared after about 3 days in the form of pustular eruptions. An 

 attenuated virus introduced directly into the heart appears to be the most effec- 

 tive way of producing inununity against glanders in experimental animals. 



The author fcmnd that in a small percentage of cases subcutaneous inocula- 

 tion of a mixture' of normal serum and active virus produced a resistance in the 

 xperimental animal. 



