VETEKINARI MEDICINE. 783 



the mesenteric and portal lymiiliatic glands. When excessively large qnantities 

 of the tubercle bacilli are fed these organisms multiply to a considerable extent 

 at the point of inoculation and even in the internal organs. In such cases it 

 iuay be possible to produce a serious toxic effect without the development of 

 the usual progressive form of tuberculosis. 



Avian tubercle bacilli were also fed to a colt (j months old. No tuberculous 

 infection took place. The animal was killed about six months after inoculation 

 and at that time no pathological changes were observed except slight phlegmon 

 and suppuration iu the right thigh. The author was unable to find any acid- 

 fast bacilli in the liver and material taken from the mesenteric glands was 

 not infectious for fowls. 



Tubercle bacilli of different orig-in with special reference to tuberculosis 

 of the alimentary and mesenteric g'lands, A. Weber and M. Taute {Tuhcrku- 

 lufiC Alb. K. G'iinlhtfitniit., IHOI, Xv. G, pi). 13-76). — In the opinion of the au- 

 thors, conclusive evidence has been obtained that tubercle bacilli of the bovine 

 type may bring about progressive and fatal tuberculous infection iu man par- 

 ticularly during childhood. In many cases of tuberculosis in man it is. quite 

 impossible to determine whether the tubercle bacilli are of human or bovine 

 origin except by making pure cultures and inoculation experiments with labo- 

 ratory animals. 



The infection of human beings with tubercle bacilli of bovine origin takes 

 place largely in childhood and as a rule is an alimentary infection appearing 

 under the form of primary tuberculosis of the intestinal and mesenteric lym- 

 phatic glands and also of the cervical glands. In this group of tuberculous 

 infections in man, tubercle bacilli of bovine origin play a very important role 

 and gain entrance to the body largely through the food, particularly cow's milk. 



Inoculation experiments with tubercle bacilli of the human type, A. Webeb 

 (Tuhcrkulosv Arh. K. Gsndhtsamt., 1907, Ao. 6, pp. 77-87).— Tubercle bacilli 

 obtained from cases of tuberculosis in man were passed through goats 5 times 

 extending over a period of 284 days, and iu another case 8 times during a 

 period of 51(5 days, through hogs during a period of 300 days and through 

 cattle 4 times during a period of GS.j days. During' these experiments no 

 change iu the virulence of the tubercle bacilli of any of the cultures was ob- 

 served and the peculiar growth and characteristics of the human tubercle bacilli 

 persisted without alteration. 



Studies of surgical cases of tuberculosis, F. Oeiilecker (Tubcrkulosc Arb. 

 K. Gsiidhtsdint.. 1907, Ao. 6', pp. S8-21Jf, pi. 1, fiys. .}). — Iu a preliminary com- 

 parison of cultures of tubercle bacilli obtained from man and cattle it was 

 found that these two types remain completely distinct when cultivated upon 

 bouillon. In all cjises it was possible to distinguish between the two tyiK^s 

 merely l)y the habit of growth aud without the use of a microscope, or resort 

 to inoculation experiments with animals. 



The author carried on a long series of experiments in the inoculation of rab- 

 bits with cultures of human tubercle bacilli obtained from surgical cases. It 

 was found that these bacilli when inoculated^in doses of moderate size are not 

 capable of producing visible alterations of the lymphatic glands in the region 

 of the point of inoculation. The rabbit, however, is not considered as satis- 

 factory an exi>erimental animal as ai*e cattle for furnishing a .'<hari> distinction 

 in the pathology of the human and bovine tubercle bacilli. 



From 50 surgical cases of tuberculosis, the author isolated human tubercle 

 bacilli in 415 and the bovine type in 5 cases. Among these 50 cases 14 were 

 tuberculosis of the cervical glands and in 4 of these cases the tubercle bacilli 

 were of bovine type. During the author's long continued experiments no sup- 



