1917] VETERINARY MEDICINE. 581 



but repeated daily injections in horses are followed by nervous manifestations, 

 marasmus, coma, and death. " The symptoms observed in experimental horses 

 following the injection of the sterile filtrate of this bacillus grown on Uschinsky's 

 medium evidence the production of a toxinlike substance as an inherent character 

 of the bacillus isolated from the oat hay, and the results from repeated adminis- 

 trations suggest a systemic cumulative action. Repeated intravenous injec- 

 tions of the bacillus washed from agar slants, sterile filtrates of the culture 

 on Uschinsky's medium, broth cultures by way of the mouth or in the form of 

 enemas produced variable nervous symptoms and death in horses and mules." 



"A somewhat similar microorganism has been isolated from the chicken excreta 

 found in the oat hay, but its pathogenicity has not yet been established. This 

 micro-organism was not isolated from two apparently wholesome forages ex- 

 amined bacteriologically, but from sorglmra silage obtained from a farm where 

 animal fatalities had occurred with symptoms resembling forage poisoning, a 

 micro-organism with somewhat similar cultural characteristics was obtained. 

 Tlie micro-organism from the sorghum silage possesses pathogenic properties, as 

 observed following inoculation of experimental horses," and reported below. 



Studies in forage poisoning, R. Graham and L. R. Himmelbkkger (Jour. 

 Compar. Path, and Titer., 29 (1916), No. 2, pp. 101-116).— In continuation of the 

 above studies, the authors report upOn an outbreak in Woodford County, Ky., in 

 December, 1915, in which losses occurred among young cattle fed grain rations 

 and silage. The symptoms in these animals consisted of emaciation, dull languid 

 appearance, incoordination in walking, loss of appetite, diarrhea, decubitus, tem- 

 perature and respiration normal, and pul.se weak. The feeding of the silage, 

 which consisted of sorghum cut about one week before placing it in the silo in 

 August, was discontinued, and no further losses occurred. 



Fourteen experiments with animals, including cattle, horses, sheep, and goats, 

 were made, in which feeding and inoculation tests were carried out with silage, 

 watery extract of silage, cultures of the bacillus, and sterile filtrates from cul- 

 tures. The bacillus isolated from the silage, but which could not be found in 

 the station sorghum silage, possessed pathogenic properties for some of the ex- 

 perimental animals. " Daily administrations of sterile filtrates of this bacillus 

 grown on a synthetic medium, introduced intrajugularly, and bouillon cultures 

 in the form of enemas produced death in horses, as did also daily drenches of 

 bouillon cultures to calves, with clinical manifestations and gross anatomical 

 changes not unlike those observed in some cases of forage poisoning. The morpho- 

 logical and cultural features of this bacillus are in every major detail analogous 

 to those pos.sessed by a pathogenic organism isolated from an oat hay respon- 

 sible for losses among horses and mules, as demonstrated by feeding experi- 

 ments," as noted above. 



The etiology of infectious anemia of the horse, Cabbe and VajliJ^e (Rec. MM. 

 V6t., 92 (1916), No. 7, pp. 19S-199; Ann. InM. Pasteur, SO (1916), No. 8, pp. 

 S8S-388; abs. in Trop. Vet. Bui., 4 (1916), No. S, pp. 12^, 125).— This is a sum- 

 mary of work conducted by the authors during the past 12 years, with references 

 to the work of others who have confirmed the authors' original findings 

 incriminating an ultravisible virus as the cause of this disea.se. The authors 

 refuse to admit the unicity of pernicious anemia of the horse and that the 

 disease is only verminous in origin, as reported by Seyderhelm and Seyder- 

 helm (E. S. R., 33, p. 681) and by Ries (E. S. R., 18, p. 584). 



Report on the investigation into joint-ill in foals existing in the Province 

 of Ontario, F. W. Schofield (Toronto, Canada: Govt., 1915, pp. 16). — This first 

 report Includes tables giving the bacteriological results in 23 cases of joint-ill 

 and the results of vaccine treatment. A specially prepared bacterial vaccine 

 containing Staphylococcus aureus, Streptococcus sp., and Bacillus abortivus- 



