1918] VETERINARY MEDICINE. 283 



by flies. In the second part the results of their investigations in regard to 

 certain phenomena, such as the production of gas and odors, the exudation of 

 fluid, and chemical changes in the tissues, which precede or accompany the 

 distintegration of the principal constituents of the body under various condi- 

 tions, are recorded. In part 3 are considered the actions of various coal-tar 

 oils and their constituents on maggots and the results of treating carcasses 

 of small and moderate-sized animals in the open. Part 4 records the results 

 of the use of creosote oil mixtures. 



Pathologic conditions noted in laboratory animals, F. O. Mann and S. D. 

 Brimhall {Joxir. Amer. Vet. Med. Assoc, 52 {1911), No. 2, pp. 195-20^, figs. 9). — 

 The autopsical findings of a number of laboratory animals used for experi- 

 mental purposes are reported. The desirability of using only normal animals 

 for experimental purposes and the importance of comparative pathology in 

 experimental work is noted. 



The treatment of infected wounds, A. Carkel and G. Dehelly (Le Traite- 

 ment des Plaies Infectees. Paris: Masson & Co., 1917, pp. 179, pis. 6, figs. 76). — 

 An explanation of Carrel's method of treating wounds in which Dakin's hypo- 

 chlorite solution is used. 



The treatment of infected wounds, A. Carrel and G. Dehelly, trans, by 

 H. Child {London: Bailliere, TindaU & Cox, 1917, pp. IX+238, pis. 6, figs. 76; 

 rev. in Vet. Jour., 73 {1917), No. 506, pp. 300. SOI; Jour. Amer. Med. Assoc., 69 

 {1917), No. 19, p. 1645). — An English translation of the above noted work. 



The antiseptics and the war, L. Gekshenfeld {Amer. Jour. PJiarm., 89 

 {1917), No. 11. pp. 487--'f96) .—A discussion of the newer anti.septics that have 

 been used in the treatment of wounds. 



Report on the use of Dakin's solution, H. E. Kingman {Jour. Amer. Vet. 

 Med. Assoc., 52 {1917), No. 2, pp. 1S5-188).— The results of the use of Dakin's 

 solution in 13 cases are reported. The technique of Dufresne (Daufresne) as 

 described by Eakins (E. S. R., 37, p. 477) was used in all the cases. 



The results indicate that in reasonably fresh wounds such as wire cuts and 

 other accidental wounds serious infection can be controlled and the time of 

 healing materially shortened. The solution has also been found satisfactory 

 for use on the arms and hands and external surfaces in obstetrical operations 

 and the removal of secundines. It has also been used as a first step in the 

 preparation of the hands and the fields of operation. 



The preparation of vaccines on a large scale, J. Cunningham, H. C. Brown, 

 and K. R. K. Iyengab {Indian Jour. Med. Research, 5 {1917), No. 1, pp. 1-18, 

 pis. llf). — This is a general description and discussion of the preparation of 

 vaccines at the Central Research Institute in India. 



Toxicity of certain preservatives used in serums, viruses, and vaccines, 

 J. P. Leake and H. B. Coebitt {Pub. Health Serv. U. S., Hyg. Lab. Bui. 110 

 {1917), pp. S5-Jf5, figs. 2). — From the results of the study reported there ap- 

 pears to be no definite minimum lethal dose of the disinfectants studied (phenol, 

 tricresol, various commercial cresols, and glycerin), since some of the experi- 

 mental animals survived doses twice the size of those which killed a consider- 

 able proportion. Considering, however, the minimum lethal dose to be the 

 amount necessary to kill 80 per cent of the animals on a given dose, phenol was 

 found to have a minimum lethal dose of 0.00037 gm. per gram weight of mouse. 

 The tricresol was found to have the same value as phenol, and the toxicity of 

 either was found not to be lessened when they were diluted Avith normal horse 

 serum. The toxicity of glycerin, calculated on the same basis, was found to be 

 approximately 0.012 gm. per gram weight of mouse. The toxicity of glycerin 

 mixed with phenol or cresol was found to be slightly higher than that of pure 

 glycerin. 



