1918.] VETERINARY MEDICINE. 585 



(Jour. Expt. Med., 26 (1917), No. 6, pp. 867-883, flgs. 10; abs. in Chem. Abs., 

 12 (1918), No. 1, p. 5i).— Continuing previous studies (E. S. R., 38, p. 379) by 

 investigating 22 additional strains of B. welchii for toxin production and 

 antitoxin treatment, the autliors have found that " the antitoxin for B. 

 welchii toxin can apparently be prepared from a single strain of the organism 

 which yields under the conditions described a high titer of toxin, and this 

 antitoxin can be employed to combat infection with or prevent infection by 

 any strain whatever of the bacillus." 



Experinieiits to determine the effect of fresh muscle and glucose on toxin 

 production and the relation of acidity to toxicity in the filtrates have shown 

 that (1) fresh muscle increases the potency of the toxin fivefold while auto- 

 claved muscle has little effect; (2) the addition of 0.2 to 1 per cent glucose 

 to beef infusion broth gives a more potent product than sugar-free broth, 

 while higher percentages lower the toxin production; and (3) there is no 

 direct relation between acidity and toxicity. 



Bacterium pyog'enes and its relation to suppurative lesions in animals, 

 A. R, Ward (Jour. Bact., 2 (1917), No. 6, pp. 6i9-628).— Substantially noted 

 from another source (E. S. R., 37, p. 276). 



The use of commercial Javelle water in the treatment of infected wounds, 

 Cazin and Miss S. Krongold (Compt. Rend. Acad. Sci. [Paris'], 165 (1917), No. 

 17, pp. 569-572). — From the results of 510 cases of wounds treated with a 

 solution of Javelle water (15 parts to 1,000) and from the action on fragments 

 of skin of this solution as compared with the Dakin-Daufresne hypochlorite 

 solution, the authors state that at the above concentration, containing 0.427 

 gm. of hypochlorite per liter, the Javelle water is more germicidal and less 

 irritating than Dakin's solution. 



On the treatment of war wounds by the combined action of visible and 

 ultra-violet radiations, C. Benoit and A. Helbronner (Compt. Rend. Acad. 

 Sci. [Paris], 165 (1917), No. 17, pp. 572-57.^).— Experiments extending over 

 two years on the use of the Cooper-Hewitt mercury lamp for treating war 

 wounds are reported. These include the treatment of atonic and ulcerated 

 wouuds, recent wounds over a larger surface, and closed and open fractures. 



A new method of general chemotherapy-oxidotherapy, Belin (Compt. 

 Rend. Acad. Sci. [Paris], 165 (1917), No. 26, pp. 1074-1076; abs. in Chem. Abs., 

 12 (1918), No. 7. pp. 722. 723).— Clinical cases are cited in which injections of 

 potassium permanganate of different strengths have been successfully u.sed 

 In the treatment of tetanus, typhoid fever, etc. Earlier exijerimental work* 

 has demonstrated the favorable effect on certain infectious maladies of the 

 injection of oxidizing substances. 



The theory advanced by the author is that by oxidation the toxins are ren- 

 dered inactive, thereby permitting the organism to combat more successfully 

 with the microorganisms themselves. " Antitoxic therapy based on oxidation, 

 therefore, would seem to be as indispensable as antimicrobic therapy in pro- 

 moting phagocytosis." As possible therapeutic agents, the author cites potas- 

 sium permanganate, sodium chlorate, sodium persulphate, ozone, colloidal 

 metals, and pinene. 



The restraining' influence of cyanid upon oxidation in arsenical dips, A. G. 

 H01.BOROW (Rhodesia Agr. Jour., 14 (1917), No. 6, pp. 733-737).— The article 

 reports the results of investigations Into the cause of the oxidation of sodium 



'Compt. Rend. Acad. Sci. [Paris], 156 (1913), Nos. 16, pp. 1260-1262; 24 pp. 1848, 

 1849; 1.58 (1914), No. 13, pp. 966-968; Bui. Soc. Cent. Med V6t., 92 (1916), No. 14, 

 pp. 203-209; 93 (1917), No. 12, pp. 244-248. 



55096°— 18 7 



