586 EXPERIMENT STATION RECORD. [Vol.38 



arsenite in dipping fluids used for ticlj killing. The arsenate thus formed has 

 only about one-half the tick-killing power of the arsenite. 



To determine whether the oxidation is the result of microorganisms, action 

 on dipping fluids of various strong disinfectants was tested. Oxidation was 

 not completely arrested by 2.5 per cent formalin, 5 per cent corrosive subli- 

 mate, 0.5 per cent carbolic acid, and 2 per cent boric acid, which would seem 

 to prove that the oxidation is not wholly due to microorganisms. Sterilization 

 in an autoclave, boiling for half an hour, and passing the original dipping fluid 

 through a candle filter also failed to arrest oxidation completely. Small 

 amounts of potassium cyaniu proved most effective. The retarding influence on 

 oxidatioji reniained constant until 0.005 per cent was reached ; below this, oxida- 

 tion increased as the amount of cyanid was decreased. 



Further investigations are to be reported later. 



The relationship between contagious pustular stomatitis of the horse, 

 equine variola (horsepox of Jenner) and vaccinia (cowpox of Jenner), D. A. 

 DE Jong (Folm Microbiol. [Delft], 4 {1016), No. 3, pp. 239-266, pis. 5; Jour. 

 Compar. Path, and Ther., 30 {1911), No. 3, pp. 2Jf2-262, figs. 5; abs. in Trop. 

 Vet. Bui., 5 (1911), No. 3, pp. 200-202).— The equine affections de.scribed under 

 the above names are first critically reviewed and reference made to outbreaks 

 in various countries. A detailed description of the symptoms manifested in 

 outbreaks of pustular stomatitis at garrisons near The Hague follows. 



Numerous experiments in the transmission of contagious pustular stomatitis 

 of horses 1o healthy horses and also to calves, rabbits, etc., are reported iipon. 

 The conclusions are as follows : " In the observed cases of contagious pustular 

 stomatitis of the horse there was an eruption in the mouth and on the skin. 

 In the experiments material collected from the mouths of the animals attacked 

 proved capable of transmitting the disease, including cutaneous eruptions. 

 This material, after it had beeri passed through Chamberland B and F filters, 

 still possessed the same infective quality. The ordinary vaccine, propagated in 

 the usual manner, was equally capable of giving the horse pustular stomatitis, 

 including cutaneous eruptions. The horse which had contracted the stomatitis 

 spontaneously was refractory to inoculation with vaccine. Two different strains 

 of the virus of contagious pustular stomatitis of the horse behaved like vaccine 

 when inoculated to the calf and to the rabbit, and in the latter Guarnieri's cor- 

 puscles were present in the inoculated cornea. Besides, the complement t&st 

 furnished corroborative evidence in support of this view. 



" The vaccine obtained by inoculating with the virus of contagious pustular 

 stomatitis of the horse could be propagated in animals with the same regularity 

 as the ordinary vaccine. This vaccine derived from the horse gave excellent 

 vaccinal pustules when inoculated into children. The revaccinated subjects 

 presented only a reaction of revaccination. The rabbits which had been inocu- 

 lated with ordinary vaccine and had shown a markedly positive reaction after 

 recovery and revaccination with the virus of stomatitis showed only a preco- 

 cious allergic (von Pirquet) reaction, whereas the control animals showed a 

 characteristic reaction. 



" We have proved that contagious pustular stomatitis of the horse is actually 

 the most frequent form of Jenner's horsepox, and that the virus of this stoma- 

 titis passes through Chamberland B and F filters. This fact was not previously 

 known." 



Anthrax. A case of Bacillus anthracis septicemia with recovery, R. R. 

 Gbaham and H. K. Detweileb (Jour. Amer. Med. Assoc, 10 (1918), No. 10, pp. 

 611, 612, figs. 2). — The authors report the successful treatment of a case of 

 anthrax in man in which the organisms were demonstrable in the circulating 

 blood despite local excision and subcutaneous injection of serum. Intravenous 



