VETERINARY SCIENCE AND PRACTICE. -497 



inflammation. Secondarily proliferation of the tissue may occur, accompanied with 

 an accumulation of mononuclear leucocytes while the polynuclear leucocytes decrease 

 in number. The jriant cells were found to arise l)y fusion of the other cells. 



Histogenesis of hematogenous tuberculosis in th.e liver of rabbits, J. Miller 

 (Beitr. Path. Amit. u. AWj. Path., SI ( 190^'), Xo. ^, pp. 347-366, pi. i).— The author gives 

 a brief critical review of the literature relating to the histogenesis of tubercles in 

 different organs of various animals. The experiments reported in this article were 

 made upon rablnts. Direct injections of virulent tubercle bacilli were made into the 

 veins of the liver and the affected rabbits were killed at various lengths of time after 

 inoculation in order to make possible a careful study of the tubercles in the liver. 

 As a result of these experiments it was found that after a hematogenous infection the 

 development of the tubercle in the liver of rabbits begins with an intravascular and 

 perivascular inflammation with polynuclear leucocytes. The first alteration of the 

 fixed tissue cells of the liver in rabl^its consists in a swelling and separation of the 

 endothelial cells of the capillaries. These endothelial cells form the epithelioid and 

 giant cells of the tubercle. It was found that a typical tubercle might arise without 

 any observable mitosis. Giant cells were found to arise by fusion of the separated 

 capillary endothelial cells. In the development of the tubercle the liver cells took 

 no active j^art. The fate of the tubercle bacilli in the liver was not determined by 

 the author. He was unable, however, to observe any leucocytes containing the 

 bacilli. 



Hematological studies on experimental tuberculosis of guinea pigs, H. 

 Claude and A. Zaky (Conipt. Read. iSoc. Biol. Puri», 54 {190;:!), Xo. 16, pp. 505-507). — 

 The authors conducted an extensive series of experiments on guinea pigs for the pur- 

 pose of determining the relative variation in the number of different corpuscles in 

 the blood at different stages in the development of tuberculosis and under the influ- 

 ence of various lines of treatment. The guinea pigs were divided into 8 lots, of which 

 1 lot was untreated, and the other 7 lots received various lines of treatment, including 

 injections of lecithin, with or without the addition of creosote or sulphate of iron. 

 The number of red and white corpuscles of various kinds in the blood at different 

 stages of the disease are presented in tabular form. 



The influence of an exclusive meat diet on inoculation of tuberculosis in 

 chickens, K. Preisich [C'enthl. Baht. u. Par., 1. Abt., 31 [1902), Xo. 15, Orig., pp. 

 749-758). — The author conducted 2 series of experiments, one in Paris and one in 

 Budapest. In the first series 9 chickens were used in the experiment, 5 of which 

 were fed exclusively on raw horse meat, receiving daily 150 gm. to 200 gm.; the 

 other chickens were fed grain. The chickens were inoculated with tuberculosis 

 from 23 to 53 days after Ijeginning the meat diet. One chicken which received the 

 meat diet died at about the same time with a control chicken, while 3 meat-fed 

 chickens remained healthy, and 3 grain-fed chickens died of miliary tuberculosis. 

 In the second series of experiments 14 chickens were used, of which 8 were fed 

 exclusively on horse meat and 6 were fed corn. The results of these experiments 

 are presented in a detailed tabular form. The influence of the meat diet noticeably 

 {prolonged the life of infected chickens, but was not sufficient to o\ercome infection 

 in any large i)ercentage of cases. 



The contamination of meat of healthy animals with tubercle bacilli 

 through nondisinfected slaughter or inspection instruments, G. Decker 

 {Zt.%-ln: Fleiach v. Mdrhhyg., 1,.' (1902), Xo. S, pp. 23.5-231).— \n these experiments 

 the purpose of the author was to determine whether in the practice of meat inspec- 

 tion or during the slaughter of animals healthy meat might become infected by the 

 instruments of the butchers or by the knives used in inspection, and also to discover 

 suitable means of preventing this infection. The results of experiments on the first 

 point were positive. Of 47 pieces of meat and meat products handled in the ordinarj^ 

 manner, it was found that 19, or 40.42 per cent had become contaminated with 



