VETEKINARY SCIENCE AND PRACTICE. (>99 



u. Pin:, 7. .1/^/., 3;.' {1902), X<>. 1, Grig., ]>p. 28-4^). — The literature relating to the 

 value of the agglutination test in the diagnosis of tuberculosis is critically reviewed. 

 The author's experiments were made on healthy and infected guinea pigs and rabbits. 

 Extensive series of experiments were conducted in 2 ways. In one series, the ani- 

 mals were infected with virulent tubercle bacilli and then treated with new tuberculin ; 

 while in the second series the experimental animals were first treated with new tuber- 

 culin, and subsequently infected with virulent tubercle bacilli. Further experiments 

 were made on healthy guinea pigs, during which the animals were inoculated with 

 ground or emulsified bacteria for the purpose of testing tlie effect of these prepara- 

 tions on healthy animals. The results of these experiments are presented in detail, 

 but the essential points may be stated as follows: The agglutination of tubercle 

 bacilli does not occur regularly in cases of tuberculosis. This reaction, therefore, 

 can not be considered at the present time as a practical means of diagnosis. The 

 tubercle bacilli may be agglutinated as a result of subcutaneous injection of Koch's 

 bacteriul emulsion in doses of a few milligrams. No favorable action of the new 

 tuberculin of Koch upon the course of experimental tuberculosis could be observed. 

 It was found that pulverized tubercle bacilli as well as the new tuberculin of Koch, 

 or bacterial emulsion, might contain active virulent tubercle bacilli. 



Causes and suggestions for the prevention of tuberculosis, H. D. Holton 

 {Siinltiir'nni, 4'-' (l'-)OJ), No. o94, 2>l'- 193-^03). — A general discussion of the means of 

 transmission of tuberculosis among human beings. It is argued that the danger from 

 the meat and milk of tuberculous animals maj^ have been somewhat exaggerated, 

 but, in the author's opinion, such danger does exist to a considerable degree, and it 

 is believed, therefore, that the safeguards which have thus far been adopted in pre- 

 venting transmission of tuberculosis by meat and milk should not be abandoned. 



Tuberculosis of the udder, A. Moser {Arch. Whi^. n. Prali. Thierh., 38 {1902), 

 No. 1-2, pji. 1-27, fgs. 11). — A review of the literature concerning the histology of 

 mammary tuberculosis is presented, in connection with a bibliography of 83 titles. 

 The author found that in mammary tuberculosis in cows the formation of new tissue 

 begun in all cases with the proliferation of the secretory e2"iithelium. This tissue 

 was subsequently replaced by cells which arose from wandering cells. While the 

 greater part of the tuberculous neomorph was found to consist of hardened lobules 

 of the glands, the cooperation of the interacinous connective tissue was of less impor- 

 tance. The newdy formed tissue undergoes necrosis, caseation, and calcification, in 

 the order named. 



Tuberculosis in the nerve centers in dogs, G. Petit {Rcc. Mfd. Vet., Paris, 

 S.ser., 9 {1902), No. 6, j'P- 1^5, 106). — Brief notes are given on the occurrence of 

 tubercular meningitis, and other forms of tuberculosis in the central nervous system 

 of dogs. 



Foot-and-mouth disease, E. Thierry (./o»r. Agr. Prat., n. ser., 3 {1902), No. 23, 

 pp. 735-739, id. 1). — A general description is given of the symptoms of the disease, 

 post-mortem findings, and of the treatments usually applied in combating this 

 plague. 



Foot-and-mouth disease of cattle and its treatment according to the method 

 of Baccelli, II. Miessxer {Deut. Mnl. WcJtiischr., 28(1902), No. 10, pp. 170, 177).— 

 The author gives a brief review of the literature thus far published on the subject of 

 intravenous inoculation of corrosive sublimate in the treatment of foot-and-mouth 

 disease. The experiments of the majority of investigators, as well as those of the 

 author, indicate that little success is to be hoped for from the use of this method. 



A study of the central nervous system in cases of the foot-and-mouth dis- 

 ease of cattle, (J. ScAGLiosi {Deut. Med. Wchaschr., 28 {1902), No. 12, pp. 197-199).— 

 Pieces of the brain and spinal cord from cattle affected with foot-and-mouth disease 

 were carefullj^ fixed and preserved for microscopic study. It was found that the 

 nerve cells underwent profound alterations as a result of infection by the disease, and 

 these changes in the central nervous svst(>m mav be utilized in diagnosing the disease 



