1018 EXPERIMENT STATION RECORD. 



shoul<l be put forth to stamp out tuberculosis in cattle, and that milk and tul)ercu- 

 lous products should be sterilized Ijefore being eaten. 



The transmissibility of human tuberculosis to cattle and goats, A. Moeller 

 {Deut. Med. WcJinscIir., £8 {1902), No. 40, pp. 718, 719).— The author conducted a 

 number of experiments, during which attempts were made to inoculate calves with 

 human tubercle bacilli by way of the mouth, by intraperitoneal, subcutaneous, and 

 intravenous injections, and by inhalation. Similar methods were used in attempts 

 to inoculate goats. During these experiments it v/as found to be impossible to infect 

 calves with tubercle liacilli of human origin by any method whatever. The same 

 negative results were obtained from sputum or pure cultures of tubercle bacilli of 

 human origin, whether administered intravenously or given by way of the mouth. 

 Similarly, tubercle bacilli of human origin which had first been passed through 

 goats failed to produce an infection in cah-es. It was found that enormous quanti- 

 ties of the bacilli could be fed to goats or be inoculated intraperitoneally without 

 producing any infection. 



Transmission of tuberculosis of man to cattle, J. Fibioer and C. O. Jensen 

 {^Berlin. Klin. Wchmclir., 39 {1902), No. 38, ]>j>. ^.S'^-^.S'tf).— Detailed notes are given 

 on the clinical history and post-mortem examination of human tuberculous patients 

 in which there was apparently good evidence of a primary infection of the alimentary 

 tract. Among 12 children who died of tuberculosis and upon whom post-mortem 

 examinations were made a diagnosis was reached indicating primary alimentary 

 tuberculosis in 2 cases. Inoculation experiments were made on calves and cows 

 with material obtained from some of these cases. It was found that the Vjacilli thus 

 obtained were i)athogenic for calves, being in some cases exceedingly virulent. In 

 all, 5 cases of tuberculosis in man furnished material for inoculation of calves, and a 

 great difference in the virulence of the bacilli was noted, ranging from completely 

 nonvirulent to very virulent forms. It was observed that the virulence of the bacilli 

 obtained from these human tuberculous patients varied according to the age of the 

 patients, being gradually weakened in the older patients. The possibility is sug- 

 gested of an attenuating influence of the human organism which manifests itself in 

 gradually weakening the virulence of tubercle Itacilli. 



The transmissibility of bovine tuberculosis to man, Kohler {Dent. Med. 

 Wchnschr., 28 {1902), No. 45, pp. 800-804). — The recent literature relating to this 

 controversy is critically discussed by the author. It is argued that a majority of 

 cases of tuberculosis in man are due to infection from other human beings rather 

 than from the products of tuberculous animals. The statistics (pioted by the author 

 are believed to furnish proof of this proposition. It is not thought desirable, how- 

 ever, to abandon all the safeguards in protecting man from possible infection from 

 animals, but it is urged that the chief attention be given to preventing the spread of 

 tuberculosis irhiw one human being to another. 



Tuberculous infection through the alimentary tract, A. Heller {Tknt. 

 Med. Wchmchr., 28 {1902), No. 39, pp. 696, 697). — Brief notes are given on a number 

 of cases in which man has apparently become infected with tuberculous virus of 

 bovine origin, and statistics are presented showing the proportion of such cases. 

 Detailed notes are given on one case of intestinal tuberculosis in a 13-year-old l)oy, 

 which was believed to be unexplainable except on the basis of infection through 

 tuberculous products. The author states, however, that this case is not unexcep- 

 tionable, since we must consider that tubercle bacilli of human origin may readily 

 be ingested into the alimentary tract along with tilth w Inch may be present on the 

 hands, especially of children. 



Inoculation tuberculosis, O. Lassar {Deut. Med. Wchnschr., 28 {1902), No. 40, 

 j>p. 716-718). — Among 108,000 patients which came under the attention of the author 

 during the past 10 years, 34 are believed by him to be undoubted cases of inocula- 

 tion tuberculosis. These cases were chiefly veterinarians, meat stampers, butchers, 



