VETERINARY SCIENCE AND PRACTICE. 301 



contains a brief review of a large number of Italian books, pamphlets, and periodical 

 articles on general pathology classified in 17 sections according to the parts of the 

 body affected by different diseases. 



Does the virus of ovine contagious agalactia pass through niters? A. Celli 

 and D. de Blasi (Clin. Yet., '27 (1904), No. 22, pp. 129-133).— A. series of inoculation 

 tests with the virus of this disease as obtained from sheep and goats convinced the 

 authors that the virus retains its virulence after being passed through filters. 



Internal mycoses, E. Bodin and P. Savoure {Arch. Para it., 8 (1904), No. 1, pp. 

 110-136, figs. 9). — Series of inoculations were made in experimental animals with 

 Ehizomucor parasiticus, Rhizopus equinus, Mucor corymbifer, Aspergillus fumigatus, A. 

 niger, and Sterigmatocystis pseudonigra. After inoculation the blood, peritoneal fluid, 

 and various organs were examined for the purpose of detecting any hyperleuco- 

 cytosis or other effect of the fungus organisms. 



It was found that when fungus spores were inoculated into guinea pigs, the leuco- 

 cytes surrounded the spores and entirely destroyed them in the case of nonpatho- 

 genic species, while in pathogenic species the spores produce local alterations when 

 arrested in passing through the capillaries. Pathogenic spores, although surrounded 

 by phagocytes, are not digested hut remain intact and finally germinate. The 

 digestion of nonpathogenic spores takes place in the macrophages or endothelial 

 cells. Immunity toward infection with mold fungi therefore depends on destruction 

 of the spores by macrophages. In these cases the theory of Metchnikoff seems to be 

 sustained. 



Mycoses in the respiratory passages, P. Lesage (Arch. ParasiL, 8 (1904), No. 

 3, pp. 353-443, figs. 14). — A long series of observations and experiments were made 

 to determine the moisture content of respired air in man and animals, and the effect 

 of contact with the walls of the respiratory passages on the germination of fungus 

 spores, particularly Sterigmatocystis nigra. 



It was found that spores placed on the tracheal or bronchial walls of birds or man 

 either do not germinate at all or more slowdy than in air saturated with water vapor 

 and at the body temperature. The normal hygrometric conditions of the respiratory 

 passages appear to have a marked effect on the germination of spores, and this fact 

 must be considered in a study of mycoses in animals or man. 



Rats, mice, and their parasites in their relation to the distribution of 

 bubonic plague, C. Tiraboschi (Arch. ParasiL, 8 (1904), No. 2, pp. 161-349, figs. 

 72). — A general account is presented of the rats and mice of Italy, with notes on the 

 species and their distribution. Descriptive biological and economic notes are also 

 given on the numerous species of fleas, lice, and mites which are known to live as 

 parasites on rats and mice. The evidence regarding the agency of these parasites in 

 carrying plague is not conclusive in any case. 



A new saccharomycosis in rabbits, II. Roger and P. E. Weil (Arch. Med. 

 Exper. et Anat. Peith., Paris, 16 (1904), No. 2, pp. 145-162, pis. 2, fig. 1).— During the 

 course of the authors' experiments, 31 rabbits were inoculated with cultures of 

 Saccharomyces lingute pilosir. The lesions thus produced varied according to the 

 method of inoculation. The chief alterations were in the kidneys, while the liver 

 was affected in only a part of the cases. It was found possible to immunize rabbits 

 by vaccinating them with the fluid in which the yeast fungus was grown. The 

 organism is easily removed by filtration on account of its large size. 



Concerning metabolism in convalescing animals, Schwexke (Arch. Exper. 

 Path. u. Pharmakol., 48 (1902), p. 170; abs. in Ztschr. Diatet. u. Phys. Ther., 7 (1904), 

 No. 9, p. 516). — Experiments with dogs are reported and discussed. 



Further studies on dourine, J. Marek (Ztschr. Tim nun!., 8 (1904), Nos. 1-2, 

 pp. 11-23; 3-4, pp. 161-178, figs. ,?).— Detailed notes are furnished on the histological 

 structure of lesions of this disease in various tissues,' such as the intervertebral 

 ganglia, extraspinal tissues of the spinal nerves, muscles, and sexual organs. 



