1030 EXPERIMENT STATION RECORD. 



birds and thorough spraying of poultry houses. In a study of roup numerous rem- 

 edies were tried, including potassium permanganate, creolin, kerosene, camphor, 

 turpentine, etc. White the permanganate of potash was found useful in combating 

 the disease in the eyes, it appeared to be useless in treating the nasal chambers. The 

 same statement may be made for creolin. Copper sulphate in a 2 per cent solution 

 and turpentine were of little avail. Kerosene gave encouraging results, but the fowls 

 which were apparently cured subsequently died. Brief notes were also given on 

 anthrax and "mad itch" in cattle. 



The saliva of rabid animals and the vaccination of sheep against rabies, 

 P. Remlinger (Compl. Rend. Soc. Biol. [Paris], 57 (1904). No. 29, pp. 309-311).— 

 For the purpose of testing the virulence of saliva of rabid animals inoculations with 

 pilocarpin were given. This drug has the power of causing an abundant secretion 

 of saliva. It was thus found possible to collect the saliva under aseptic condition. 

 Saliva thus obtained from different animals was inoculated into rabbits, guinea pigs, 

 and other experimental animals in considerable numbers. No case of rallies 

 resulted. When a large quantity of such saliva was used in inoculation experiments 

 it had no effect in producing immunity toward rabies in the inoculated animals. 



Recent work on rabies, P. Remlixger {Bui. Inst. Pasteur, .' (1904), Nos. in, 

 pp. 753-704; 20, pp. 793-800). — An outline is presented of results obtained by inves- 

 tigations of various phases of rabies. Notes are given on the methods of penetration 

 of rabies virus into susceptible animals, the rabies corpuscles of Negri, filtration of 

 rabies virus, rabies toxin, Pasteur treatment for the disease, and symptoms, diagnosis, 

 and pathological anatomy of rabies. A brief criticism is also given of the theory of 

 Sinn regarding the attenuating effect o 1- dogs and other carnivorous animals upon 

 rabies virus. 



Negri's corpuscle and the rapid diagnosis of rabies, P. Stazzi ( Clin. Yet., 27 

 (1904), Nos. 42, pp. 249-254; 44, }'!>■ 201-205; 46, pp. 273-277) .—During the course 

 of the author's investigations it was found possible to recognize Negri's corpuscles 

 with considerable ease, and to make a comparatively rapid diagnosis of rabies. The 

 occurrence of these corpuscles and pathological alterations in the surrounding tissue 

 are briefly described. The literature of the subject is discussed in connection with a 

 short bibliography. 



Immunity in cases of piroplasmosis in dogs, A. Theiler (Centbl. Bait. \i. 

 Par., 1. Alt., Ovig., 37 (1904), No. 3, pp. 401-405). — Dogs which have resisted an 

 attack of piroplasmosis remain permanently immune to the disease thereafter. The 

 organism of the disease, however, is always found in their blood, which remains 

 virulent for susceptible dogs. Experiments were made by the author for the pur- 

 pose of determining whether dogs could be overimmunized, so as to obtain sera with 

 preventive action toward the development of piroplasmosis. During these experi- 

 ments it was found that the serum obtained by overimmunizing dogs with the defibrin- 

 ated blood of sick animals possesses considerable preventive action. The blood of 

 an overimmunized dog has a pathogenic effect whether defibrinated or not. The 

 serum of treated dogs contains a preventive substance which is not destroyed by 

 subjection to a temperature of 55° C. The mechanism of the production of a pre- 

 ventive serum in immune dogs appears to take place according to the same laws 

 which are concerned in the process of immunization by means of bacteria. The 

 only essential difference consists in the fact that the blood of highly immune dogs 

 remains virulent. 



Variation in the hooks of the dog tapeworms, Taenia serrata and T. seri- 

 alis, E. C. Stevenson and C. C. Engberg (Studies Zool. Lab., Univ. Nebraska, No. 59, 

 pp. 409-448, ]>ls. 6). — This article was prepared as a thesis for submission at the 

 University of Nebraska. The material was collected chiefly from dogs in the 

 vicinity of Lincoln, Nebraska. The authors studied the position and attachment of 

 the hooks of both species of tapeworms and gave attention also to the investigation 

 of the function of the hooks, the variation in size and shape, and the life history of 



