§ 5 



REACTION TO URINE 



37 



period of pregnancy. Luteidin thus differs clearly from preg- 

 nanediol and estrone, the secretion of which increases con- 

 siderably during pregnancy. During pregnancy luteidin is 

 no longer secreted cyclically, as is apparent from Fig. 42. 



3400 

 3000 

 2600 

 2200- 

 1800 

 1400 

 1000 

 600 



AU. daily luteidin excretion 



in o pregnant woman 



\I 



^ 



\r^ 



{/ 



U 



kr 



^ 



2 4 6 8 10 14 16 20 24 28 32 36 



AU 



Fig. 42. Daily luteidin excretion in a normal pregnant woman during 



6 v/eeks. Against this, the luteidin concentration per 3 ml urine. No 



periodicity observable in the excretion. 



Here the daily urine of a pregnant woman was examined. 

 The luteidin secretion in the normal cycle during preg- 

 nancy and lying-in is given again in Fig. 43. We do not 

 know of any sexual hormone from which a curve of this 

 kind could have been obtained. This supports our assumption 



AU 



ovulation 



pregnancy 



partus 



Fig. 43. Schematic representation of the luteidin concentration in 3 ml 

 urine during a period of 28 days; half a period (14 days); subsequent 

 pregnancy, and lying-in. 



