88 



FOLLICULAR DERIVATIVES IN VERTEBRATES 



III 



^' 



\^-sS 



bloodvessel 





the CO. 



granuloso^^ ^ 



secretion^ , 



of 7&^ '<, \ 

 9ro/?.fe//sl% ^„,»>-- 



invodedj^ZZ 

 grance//c 

 filled with * 

 ovidudin 



follicular — ^ 

 cell-pearls^^ 





remnants jS '- 

 oolemma &«!» 



theco 



^blood 

 Vessels 



QE?"5-V;^ 



/^ '?S^ 



3. 



remnants 

 oolemma 



Fig. 66. Corpus luteum, /?-stage, ready to secrete; the egg has disappeared, 



its cavity being filled with granulosa-lutein cells; invasion of theca tissue 



and bloodvessels. 



Meanwhile the granulosa cells have completely incorpor- 

 ated and assimilated the ovular substances. The remaining 

 inner space of the ovum consists of liquid, insofar as it does 

 not still contain granulosa cells (Fig. 66, left). At this stage 

 of development of the corpus luteum all granulosa cells are 

 seen to possess a foamy plasm rich in vacuoles. Apart from 

 a somewhat denser plasm in the neighbourhood of the 

 nucleus, the numerous vacuoles occupy almost the entire 

 cellular space (Fig. 66). They are of different sizes, lie 

 adjoining one another, and are separated by thin walls. 



Our cytological investigations, which are not yet com- 

 pleted, have so far shown that in the base of the granulosa 

 cells new substances are formed with the aid of mitochondria 



