VETEEIlSrARY SCIENCE AND PRACTICE; 591 



made on experiments upon rab])its wliich were inociilatcMl intravenoiij^ly. From 

 these experiments it is ooncluded that the tubercle bacilhis l)y its toxic action destroys 

 the epithchal cells and connective tissue. At iirst the newly formed cells are affected 

 only in so far as the connective tissue and vascular tissue fail t(j l)e formed. Ulti- 

 mately these cells are comjiletely destroyed and caselied. 



The distribution of the lesions in generalized tuberculosis, J. McFadye.\n 

 {Jour. Conip. Path. (Oid Ther., 14 [1901), Xn. 1, j>p. 1-1 J) . — Tliis jiaper contains a report 

 on experiments with reference to the agency of tiie l)l()od circulation in the generali- 

 zation of tuberculosis. Ten cattle were inoculated intravenously with virulent cul- 

 tures of tuberculosis and careful post-mortem examinations were made after varying 

 lengths of time. In all cases the lungs contained numerous tubercles, Avhile tubercles 

 were found in the liver and kidnev^s in only 3 cases and in only 1 case in the spleen. 

 The best evidence of generalization of the disease is believed to l)e the presence of 

 tubercles of nearly equal sizes scattered throughout the entire substance of the lung. 

 The evidence of generalized tuberculosis from an examination of other organs is 

 usually not relialile. In cases of generalized tuberculosis the kidneys, liver, or 

 spleen may be entirel)' free from tubercular lesions which can be recognized by the 

 naked eye. Tlie tubercles which are found in the liver, spleen, kidneys, and lym- 

 phatic glands are, as a rule, due to lymphatic action and not to the agency of the 

 biood circulation. Tubercle bacilli are readily carried in the lymphatic vessels 

 downward from the center of infection. During the post-mortem examinations 

 abundant evidence was noticed of the process of recovery which was taking place in 

 the older tubercles. An infectioai of the lymphatic system was noted in 4 of the 10 

 cases. 



Tuberculous mening-itis in cows and the infection of the fetus, H. Thon 

 {Deut. Thiemrztl. WcJmschr., 9 {1901), No. 11, pp. 107, IDS).— The author gives 

 details of the clinical symptoms and post-mortem findings in a cow infected with 

 tuberculo.sis. The symptoms indicated an invasion of the brain by the tubercle 

 bacillus, and the post-mortem examination revealed the presence of pathological 

 changes in the cerebral mem))ranes. Tubercles were also found on the sui'face of 

 the fetal liver. 



Cattle inspection and the tuberculin test, G. B. .Jobsox {Jour. Comp. Med. and 

 Vet. Arch., 22 {1901), No. 3, pp. 144~148). — The author discusses the influence of 

 cestrum, stabling in warm weather, age, and other circumstances, upon the tempera- 

 ture of cattle, with reference to difficulties of diagnosis from the tuberculin test. The 

 temperature of 10 cattle under 1 year of age averaged about 0.4° higher than that 

 of 10 other cattle over 3 years of age. All cattle were free from tuberculosis. The 

 author believes that the absence of a reaction to a second test of tuberculin is not 

 conclusive in showing that the animal is free from tuberculosis. Several cases are 

 noted in which there was a failure to react in animals which were known to be 

 tu])erculous. A brief discussion is given of the difficulties in arriving at a satisfactory 

 estimate of the value of condemned animals. 



Results of seven years' work in testing with tuberculin, F. G. Meyer 

 {Maanedsskr. Dijrheger, 12 {1901), No. 11, pp. 409-418). — The author reports in detail 

 on the condition of cattle in Norway with reference to the prevalence of tuberculosis. 

 The results of tuberculin tests are brought together in tabular form, from which it 

 appears that from 1893 to 1900, 11,686 cattle were tested in 402 herds, and 20 per 

 cent were found to be tuberculous. Brief notes are also given on the prevalence of 

 tuberculosis among calves. 



Tuberculosis of cattle and the Pennsylvania plan for its repression, L. 

 Pe.\rsox and M. P. Ravenel {Penusi/limuu Dept. Agr. BuJ. 75, pp. 262). — This is a 

 reprint from Pennsylvania Department of Agriculture Report for 1899 (E. S. R., 12, 

 p. 686). 



