334 EXPERIMENT STATION RECORD. 



The testimony ol'tlie foreign tuberculin was substantiated by autopsies 

 ill L'l out of I'S instances, or excluding those animals that received the 

 irnpoited lymph after having been injected with the stronger domestic 

 tuberculin, the foreign article gave correct indications in 18 out of 21 

 cases, or S() per cent. 



Jn addition to the animals used in the above comparison 12 others 

 were inoculated, making .">() subjected to the test. 



"Or these, 25 reacted and the remainder were declared healthy. The autopsy 

 record shows that in every one of the 25 reacting animals evident lesions of the 

 disease were discovered. 



"Of the 5 animals that tailed to react 3 were slaughtered, and 1 of these was 

 found to he somewhat diseased, so that in the 28 cases where j)o.s/-»*or/cms were 

 made it [tuherculin] failed only once." 



A physical examination by a veterinarian gave correct diagnoses in 

 only out of 15 cases. Of 2(> tuberculous anin'ials 3() per cent showed 

 tuberculous lesions in the pharyngeal and submaxillary lymph glands, 

 81 per cent in the bronchial and mediastinal lymj)li glands, 44 per cent 

 in the right lung, ~i2 ])er cent in the left lung, and 48 per cent in the 

 mesenteric glands. "Such a preponderance of cases showing uu- 

 (h)iil)tc(l pulmonary infection nulicates strongly the danger that closely 

 lionsed annuids undergo, if the disease is once introduced into their 

 midst." 



Of 8 calves slaughtered, aged from 7 weeks to months, 7 were 

 decidedly tuberculous; 5 "were more or less diseased in the abdominal 

 organs, indicating a probable contamination from infected food or drink. 

 As the milk is now known to have contained germs of this disease, 

 there is hardly any questi(m but that the intestinal infection was due 

 to the milk fed them during this short period." 



The author recommends the use of tuberculin in herds supplying 

 consumers with iiulk and in the purchase of additions to any healthy 

 herd. ''The probability of a sufficiently large number [of tubercle 

 bacilli] being incorporated into butter or cheese is so small as to reduce 

 this chance for infection to a mininuim." 



A case of glanders in man apparently cured by mallein, A. 

 BoNOME {J)ci(t. titcd. Wochoisrhr., is'Ji, No. 37, p. 7:^5).— A lad. about 

 17 years old, who had contracted a severe case of glanders from 

 woiking about horses that had profuse nasal discharges, was ti-eated by 

 the author with injections of mallein and a cure apparently effected. 

 The first 7 injections of 3 drops in 1 cc. of sterilized water, given at 

 inteivals of 2 or 3 days, caused an increase of about 2 to 3^ C. ni the 

 temperature, except in the case of the second and fourth injections. 

 The reactions following the iujections were similar to-those observed in 

 The horse. Fourteen more injections were made, using C drops of 

 mallein, witli a diminished reaction. Two months after the first injec- 

 tion the patient was dismissed from the hospital apparently cured. 



This is the first case on record where mallein has been used for curing 

 the disease in man, althougli cures have been accomplished in horses by 



