DISCUSSION 



39 



is, in the chronic period — often differ considerably in the rate of development 

 and the degree of manifestation. Late radiation reactions appear to be irre- 

 versible. 



The second factor I wish to emphasize is the importance of the tumor bed in 

 the therapeutic irradiation of a tumor. Consideration of adequate protection 

 for the vascular-connective-tissue tumor bed is as important as destruction of 

 the tumor itself. 



