CINCHONA OFFICINALIS. 163 
other medicine in the world could have produced such an 
effect, because no other is capable of causing this symptom. 
“ Quinine is seldom effectual, unless it disturbs the rest of the 
patient at night, as it does that of persons in health who make 
trial of it. 
“There are some cases of suppuration in the lungs, but few in 
number, principally such as are accompanied by shooting pains 
in the breast, excited or increased by external pressure, that 
have been cured by Quinine, under the condition of resem- 
blance in other symptoms. ‘Then one or two weak doses, 
separated by a long interval, have produced the cure. 
“ There are also some few cases of jaundice resembling the 
symptoms of Quinine. ‘These yield as by magic to one, or at 
most two doses of the tincture, and health is completely 
restored. 
“ An intermittent fever must bear a very close resemblance to 
the Quinine symptoms, for this medicine to be the true remedy 3 
in which case the disease is conquered by a single dose. But 
itis best to give it immediately after an attack, before nature 
has had time to prepare the next. Whenever physicians aim, 
by large doses, to cut short a fever to which it is not appropriate, 
they give it just before the attack—the period when that 
violence, so much to be dreaded in its after-results, produces 
the most certainly the effect expected from it. 
“Quinine makes a permanent cure of an intermittent marsh 
fever only if the patient can change the air during the treatment, 
and until his strength is restored. If he remain in the marshy 
effluvia, the cause of his illness continues to act upon him, and 
the remedy, though repeated, produces no more effect. In the 
same manner, the complaints caused by the abuse of coffee 
yield readily to the proper remedy, but reappear from time to 
time, if that beverage be not discontinued. 
“ But how can we reconcile the extraordinary manner in which 
Quinine has been employed, with the idea of substituting other 
