554 EXPERIMENTAL RESEARCHES WITH CHICKEN-CHOLERA MICROBES, 



required to kill either fowls or pigeons, did not show any consider- 

 able difference in either the one or the other case, so that we may- 

 say here, as we did before, that the degree of virulence was at the 

 end of the experiment practically the same as at the beginning. 



Notes on the Body Temperatures of Rabbits inoculated ivith the 

 Mic7'obes of Chicken-cholera. 



In connection with the experiment conducted with a view to 

 determining the degree of virulence of the bacteria of chicken- 

 cholera, when made to pass though the bodies of rabbits in twenty 

 generations of two rabbits for each, 1 have been able to make a 

 series of observations regarding the body-temperatures of such 

 rabbits.* 



In a number of cases the temperature was taken, at intervals, 

 from the time of inoculation (immediately before it) until death 

 (immediately after it) ; in several instances only up to some time 

 before death. 



These observations are put together in Table V., at the end. 



From the data given in this table we may reasonably conclude 

 that— 



1. As a priori intelligible, the septicaemia which is the result 

 of transmitting virulent chicken-cholera bacteria into rabbits, 

 is associated with a gradual increase in the body-tempera- 

 ture, which in its maximum was found to difler from the 

 initial temperature by 2*5° C. in one case (No. 8), by 

 1-95° C. in another (No. 2), by 1-9° C. in a third (No. 7), 

 by 1*8° C. in two others (Nos. 10 and 16), while in the 

 remaining cases the difference was less. 



2. This maximum, as a rule, is noticed some little time before 

 death. 



The difference between the initial body-temperatures (taken 

 immediately before inoculation) and the final body-tempera- 

 tures (taken immediately after death) may also be seen, in the 



* The observations were made by means of an ordinary clinical ther- 

 mometer which, after having been oiled with ol. amygd. dulc, was intro- 

 duced into the anus to the length of between six and seven centimetres. 



