LIFE AND WORK OF FELIX HOPPE-SEYLER. 545 



Baumann, Froriep, Gaelitgens, Parke, Salkowski, Zalesky, Lobiscli, 

 Tolmatsclieff, Polz, Diakonow, Liebreicli, Lubavin, Manassien. 

 Here lie remained for ten years, until in 18Y2 lie went to Stras- 

 burg to take tlie cliair of physiological cbemistry, the first and 

 only professorship of its kind in Germany. In Strasburg he spent 

 the remainder of his life, and here, as in Tubingen, many students 

 came to him, among whom were Kossel, Hoffmeister, Neumeister, 

 Frederiq, v. Jaksch, Ledderhose, v. Mering, Mauthner, v. Udransky, 

 Popoff, Rajewsky, Sokoloff, Howath, Ilerter, and Giacosa. 



In 1864 Hoppe was formally adopted by Dr. Seyler, and there- 

 after took the name of Hoppe-Seyler. In 1858 he married Agnes 

 Franziska Maria Borstein, by whom he had one son, Georg Hoppe- 

 Seyler, now professor of medicine in Kiel. In appearance Hoppe- 

 Seyler was an erect, vigorous, active man, above medium height. 

 Although at the time of his death nearly seventy years of age, his 

 hair was not yet gray, his step was still youthful and elastic, and 

 he appeared yet to have many years of life before him. He was 

 eminently what the Germans call " liebenswurdig " — kindly and 

 sympathetic, especially toward his pupils, whom he made his friends. 

 With all his kindliness, however, Hoppe-Seyler, like Huxley, had 

 little patience with half truths or errors, and he possessed a sharp pen, 

 v/hich, in truly German fashion, told the whole truth about one 

 unfortunate enough to incur his displeasure. 



The scientific work of Hoppe-Seyler extended over forty years. 

 His contributions to science are embraced in some hundred and 

 forty-six separate papers. He was the author of a handbook of 

 physiological and pathological chemical analysis, which has had six 

 editions, and is still the best book of its kind extant. In the years 

 1877 to 1881 he published his celebrated text-book of physiological 

 chemistry, which still remains as a monument to his industry, to the 

 wide scope of his knowledge, his keenness of perception, and his 

 power of correlating facts. Though many of the conclusions con- 

 tained in the work have been modified by more recent investigation, 

 the book stands unique among similar productions as the most ex- 

 haustive treatise on the chemistry and chemical changes of the animal 

 and plant kingdom ever attempted. 



The range of subjects in which Hoppe-Seyler published observa- 

 tions, outside his biochemical work, is remarkable, and includes 

 botany, mineralogy, geology, chemistry, and physical diagnosis. 

 He detected the presence of the newly discovered element, in- 

 dium, in wolframite, and he devised a spectroscopic test for 

 manganese, which is one of the most delicate known, and is still 

 called Hoppe-Seyler's manganese test. Throughout his life he 

 took a keen interest in mineralogy and geology. In 1865 he 



VOL. LIII. — 38 



