5] STUDIES ON PROTEIN MICROSTRUCTURE 89 



thus indicate not only an extensive similarity in the structure of the two 

 hemoglobins examined, but also either the repetition of certain peptide 

 sequences involving the basic amino acids, or, more probably, the exist- 

 ence of several identical units in the molecules of these proteins. This last 

 assumption is borne out by the work of Reichmann who found that under 

 certain conditions the haemoglobin molecule may dissociate into four parts. ^^ 

 In this review, I have attempted to demonstrate the principles on which 

 we base our approach to the problem of protein microstructure and some 

 of the first results of this approach. 



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