348 



INDEX 



Lactogenic hormone, see Prolactin 

 ß-Lactoglobulin 



configuration and pH, 57 

 deuterium exchange, 32 

 polymerization, 61 

 viscosity, 38 

 Leucinaminopeptidase 



action on chymotrypsinogen, 164- 

 167 

 enolase, 338-340 

 j3-melanotropin, 307, 308 

 mercuripapain, 192-199 

 poly-DL-alanine, 33 

 localization of amide groups in 

 peptides by, 192, 218-219 

 Lysozyme 



action of pepsin on, 285-288 

 chymotrypsin on, 280-285, 289 

 trypsin on, 227-228, 280-285, 289 

 configuration and pH, 59-60 

 dialysis rate, 108, 110 

 disulphide bonds, oxidation, 282- 

 285 

 reduction and carboxymethyla- 

 tion, 226-228 



a-Melanotropin 

 structure, 334-335 

 relation to corticotropin, 335-337 

 ß-Melanotropin 



structure, 303-307, 333-334 

 properties, species differences in, 



309 

 relation to corticotropin, 313, 335- 



337 

 Myoglobin 

 amino acid composition, 145-146 

 elect rophoretic heterogeneity, 140- 



143 

 heavy atom derivatives, 129-132 

 molluscan, 144-147 

 oxygen dissociation curves, 141- 



142, 145 

 physico-chemical properties, 144- 



147 

 X-ray analysis, 127-135 



Neochymotrypsinogens, 159-163 

 Nucleic acid, 234, 250, 256, 262, 272 



Optical rotation, 1 7 

 and chymotrypsinogen activation, 

 155 



y-globulin, 58 



ribonuclease, 234-235 

 effect of guanidine on, 236-237 



and trypsinogen activation, 169, 

 170 

 Ovalbumin 



configuration and pH, 59 



dialysis rate, 108 



disulphide bonds in, 45 



viscosity, 38 

 Ovomucoid, dialysis rate, 108 



Papain 



action on antiovalbumin, 290 

 amino acid composition, 187 

 autolysis, 199, 200 

 chromatography of, 197, 200 

 cysteic acid peptides from, 186- 



187 

 homogeneity, 183-184 

 kinetics, 200-206 



leucinaminopeptidase on, 192-199 

 mechanism of action, 203-208 

 mercury derivative, 184 

 oxidized, action of trypsin on, 188- 



192 

 pH, effect on activity, 200-203 

 physico-chemical properties, 183- 



184 

 sulphydryl groups and activity, 



184-186, 191, 202-206 

 Pepsin 



action on corticotropin, 310-312 

 lysozyme, 285-286 

 ribonuclease, 212-213, 233, 235 

 autolysis, effect of urea on, 179-181 

 configuration and pH, 55, 57 

 dialysis rate, 108 

 viscosity, 38, 55, 57 

 Peptidases, see Carboxypeptidase and 



Leucinaminopeptidase 

 Peptide bond, configuration of, 18-21 

 Peptides (see also under individual 



proteolytic enzymes and pro- 

 teins) 

 basic, 86-89 

 comparison of composition from 



different proteins, 79-84 

 cysteic acid, 84-85, 186-187, 200, 



229-230, 283-284 



