GENERAL INDEX 



349 



Sulfanilamide (cout.) 



inhibition of antibacterial action, 

 198, 218, 219 



therapeutic value, 226 

 Sulfapyridine, 205-206, 227 

 Sulfathiazole, 204, 227, 229, 233 

 Sulfhydryl groups, 197 

 Sulfonamide 



compared with clavacin, 134 



compared with penicillin, 205, 227- 

 230, 234 

 Sulfur compounds, 53, 160 

 Suppressor, defined, 271 

 Surface tension, 197 

 Symbiosis, 14, 38-41, 43 

 Synergism, 40, 206 

 Syphilis, treatment with penicillin, 234 



Tannic acid, effect on actinomycin, 219 

 Temperature for growth of antagonists, 



Testing antagonistic action, methods. 

 See Methods of testing antagonis- 

 tic action 



Testing in vivo activity, methods, 78 



Tetanus organism, survival of, 29 



Texas fever, i 7 



Ticks, bactericidal action of, 1 49-1 50 



Tissue culture, 200 



Tolu-/>-quinone, 70, 77 



Toxicity of antibiotic substances, 122, 

 i57-i59> 161, 245 



Toxin destruction, 223 



Toxin production, lOO 



Toxoflavin, 160, 170, 171, 270 



True antagonism, 47, 49 



Trypanosome parasites, 1 47 



Tubercle bacillus, 30, 34-36, 135 



Tuberculosis, treatment with extracts of 

 A. fumigatus, 133, 244 



Tumors, 154-155, 222 



Turbidimetric method of measuring 

 antibiotic activity, 75-76 



Typhoid organism, 90, 91, 213 

 as antagonist, 97 

 in soil, 29-30, 32-34, 80-81 



Typhus rickettsiae, 234 



Tyrbcidine, 67, 167-17 1, 270 



Tyrocidine (cout.) 



chemical nature, 53, 159, 160 

 compared with gramicidin, 192 

 crystals. Fig. 18 (p. 170) 

 eifect on bacteria, 70, 192, 195, 206 

 hemolytic effect of, 239, 240 

 mode of action, 197, 199-202, 216 

 therapeutic value, 230, 237-243 

 toxicity, 245 



Tyrosinase, 171 



Tyrothricin, 68, 76, 87, 167-171, 270 

 antiluminescent activity, 77 

 chemical nature, 159 

 compared with actinomycin, i 20 

 compared with protamine, 217 

 differentiation of bacteria by, 220 

 effect on bacteria, 70, 77, 190, 206, 



217, 237-243 

 effect on fungi, 141 

 hemolytic effect of, 200-201, 239, 



240 

 inhibition of, 219 

 mode of action, 199-202 

 therapeutic value, 230, 237-243 

 toxicity, 245 



Udder infections. See Bovine mastitis 



Urinary infections, 234 



Urine, human, bacterial composition of, 



21 

 Utilization of antibiotic substances. See 



Disease control 



Violacein, 159, 270 



Viruses 



antagonisms among, 153-154 

 inactivators of, 152-153 



Vitamins, 12, 196, 219 



War-time surgery, 226 



Wastes, human and animal. See Human 

 and animal wastes 



Water 



as culture medium, lO-ii 



as habitat of microorganisms, 1-2 



Wheat, diseases of, 247, 248, 251 



