SELECTED PAPERS 

 TABLE XI 



Energy-rich phosphate bonds 



istry has always been that in many cases the conversion of part of the 

 substrate into some assimilatory product seemed to require reactions 

 in which the free energy of the system showed an increase. This applied 

 for instance in the production of fat from glucose. In order to explain 

 this, it was rightly emphasized that the conversion was always coupled 

 with a second conversion marked by a significant decrease in free 

 energy, as for instance the respiration process. But the way in which 

 the cell succeeded in putting the energy of one chemical reaction at the 

 disposal of a second one has for a very long time remained obscure. 



Lipmann's discovery of the so-called energy-rich phosphate bond 

 has more or less solved this problem. This investigator has definitely 

 shown that several organic phosphate compounds which are quite 



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