MALARIA IN GENERAL 353 



Some idea of the variety of malaria problems available for 

 study and the amount of work being done on this subject can be 

 obtained by reviewing the papers abstracted in the Tropical Dis- 

 eases Bulletin. For example, in a single number (Vol. 26, No. i, 

 Jan., 1929) there are listed about 125 papers. These deal with 

 almost every problem mentioned above and with many others. 

 Some of them are as follows : factors influencing the geographical 

 distribution of malaria, the relation between spleen and parasite 

 rates, species of mosquitoes as vectors of malarial organisms, the 

 validity of Plasmodium tenue, the early appearance of gametocytes 

 during infections, the loss of gametocytes in strains used for 

 therapeutic purposes, the relative numbers of gametocytes before 

 and after treatment with quinine, the relation between the number 

 of gametoc}1:es and the number of oocysts, blood destruction in 

 malaria, parthenogenesis of malaria parasites, the incubation period 

 in malaria, the effects of the sugar content of the blood on relapse, 

 the significance of blood groups, relations of malaria to other 

 diseases, the effects of quinine, plasmochin and other therapeutic 

 agents, leucocyte formula, precipitin test, transmission experi- 

 ments with human malaria to lower animals, origin of malarial 

 pigment, methods of treatment, congenital malaria, control of 

 malaria in various localities and under various conditions, and fac- 

 tors involved in a malarial attack. It is safe to state that more work 

 is being done on malaria and its causative organisms than on any 

 other disease due to animal parasites. 



