PERIODICITY IN MALARIA 



403 



the sexual forms in view of the fact that Hartman (1927&) stated 

 that the asexual forms tended to disappear from the peripheral 

 blood as they do in P. falciparum. Hartman also stated that the 

 cycle was approximately twenty-four hours, unless, as seemed un- 



A5EXUAL CYCLE 



Parasite'',- 

 Nucleus'' ' 



Red Cell 

 "Nucleus of Red Cell 



SEXUAL ^STAGES.presGnl at al! hours 



Microgametocyles Macrogametocytejs 



Fig. 28.— Representation of the cycle of reproduction in bird malaria show- 

 ing changes in size. Outlines of the asexual stages of the parasites within 

 the nucleated red cells, showing nuclei and pigment granules, made at four- 

 hour intervals during a consecutive period of twenty-four hours. In addition, 

 outlines of three microgametocytes and three macrogametocytes, which 

 occur in small numbers at all hours throughout the infection. X 1500. (From 

 L. G. Taliaferro, 1928.) 



