SUBJECT INDEX 



1015 



Cholesterol, absorption, 362-365 

 acetone carbons in, 182, 382, 383 

 androgens from, 409, 410 

 antibacterial action of unsaturated 



acids, and, 870 

 atherogenic action, 371 

 bile acids from, 405, 406 

 biosynthesis, 377-401 



effect of age, 390 



of cholesterol intake, 390, 391, 398 



of diabetes, 41 



of fat, 392, 393 



of hormones, 37, 393-395 



of pH, 393 



from acetate, 261, 270, 279, 380-382 



from acetoacetate, 383 



from ethanol, 382 



from isovalerate, 384 



from squalene, 323, 324, 382, 384r-388 



in embryo, 37 



site of, 397-401 

 carcinogens and, 357 

 changes in g.i. tract, 369, 370 

 combination with protein, 371 



with imsaturated fatty acids, 371 

 7-dehydrocholesterol from, 410 

 dehydrogenation, 658 

 destruction by bacteria, 402-405 

 discovery, 361 

 effect of bile salts, 363-365 



of dietary fat, 363 



of hormones, 365 



of phospholipids, 365 



of phytosterols, 364, 416, 417 



of vitamin E, 365 

 effect on phospholipid metabolism, 60 

 effect on thyrotoxicosis, 408, 409 

 estrogens from, 409, 410 

 excretion in feces, 369, 378, 402, 412 



in urine, 414, 415 

 fat emulsion stabilizer, 206 

 function, 419, 420 

 hydrogenation in g.i. tract, 411 

 7-hydroxysterols from, 410, 411 

 in blood, 370-377 



in liver, 155, 798 (see also Liver, choles- 

 terol) 

 metabolism, 401-415 



Cholesterol (continued) : 

 effect of EFA, 824-826 



oxidation, 412-415 



pregnanediol from, 407 



requirement for insects, 378-380 



steroid hormones from, 418 



transport, 368, 369 



turnover, 405 

 Cholesterol ester, absorption, 363, 365, 

 368 



in blood, 370 



effect of avidin, 396 

 effect of thyroid, 376 



in liver, 825 



in lymph, 368 



relation to ketonemia, 149, 150 



site of synthesis, 400, 401 

 Cholesterol ester: free ratio, 372 



effect of thyroid on, 376 

 Cholesterol esterase, 363, 365 

 Cholesterol: lecithin ratio, 372 

 Cholesterol: lipid P ratio, 372 

 Cholesteryl acetate, as required for insects, 



378 

 Cholic acid, bacterial oxidation of, 404 



from cholesterol, 405, 406, 420 

 Choline, acetylation, 15, 28, 267 



action in EFA deficiency, 818 



deficiency, 250, 251 



effect on vitamin A storage, 531, 

 592 



effect on cholesterol absorption, 365 

 fatty livers, 60 

 synthesis, 396 



effect on fat oxidation, 202 



excretion, 245 



from ethanolamine, 246, 247 



from formate, 280 



from histidine, 286 



from lecithin, 236 



from serine, 286 



from sphingomyelin, 237 



in phospholipids, 52, 57, 247, 249 



ketonuria in deficiency', 146, 157 



lipotropic effect of, 59, 62-64 



metabolism, 244, 245 



oxidation, 239-244 



synthesis, 51, 64-67, 242 



