1034 



SUBJECT INDEX 



Jaundice, destructive, carotene absorption 



in, 425 

 lutein absorption in, 430 

 Jojoba oil, effect on vitamin A absorption, 



435 



K 



Kapokseed, EFA in, 827 

 Keratomalacia, 596, 601, 602, 604 

 Ketene, as "active acetate," 14 

 a-Keto acids, metabolism of, 301-302 

 i3-Keto acids, condensation with oxaloace- 

 tic, 167 

 in fatty acid oxidation, 76, 86, 292, 



294 

 metabolism, 302, 303 

 oxidation, 105 

 ^-Ketobutyric acid, 94 



reduction of, 302 

 a-Ketobutyric acid oxidation, 106 

 /3-Ketocaproic acid, 75 

 a-Ketocaproic acid oxidation, 106 

 /3-Ketocaprylic acid, reduction, 302 

 6-Ketocaproic acid, 304 

 7-Ketocholesterol, 410, 411 



activation in vivo, 657 

 Ketogenesis, 1 19 



rate of spontaneous, 178 (see also Kelo- 

 sis) 

 Ketogenic: antiketogenic ratio, 163, 164 

 Ketogenic substances, 120, 123-139 

 a-Ketoglutarate, 301 



effect on fatty acid oxidation, 101 



on lipogenesis, 19 

 formation, 168 

 from acetate, 271-274, 279 

 in Krebs cycle, 171, 305, 306, 314 

 ketogenic action of NH4CI, and, 143 

 i3-Ketohexanoic acid, dehydrogenase ac 

 tion on, 118 

 oxidation of, 303 

 /3-Ketohexanoyl-CoA, 107 

 /3-Ketoisocaproic acid, oxidation, 303 

 a-Ketoisovaleric acid, 135 

 Ketolysis theory, 164, 165, 175, 178, 179 

 Ketolytic effect, 45, 127 



of extrahepatic tissues, 198, 199 



Ketolytic substances, 121 (see also 



Antiketogenic substances) 

 Ketone bodies, as fatty acid oxidation in- 

 termediates, 121 

 excretion, 71, 72, 77, 139-146 



effect of glycerol, 45 

 extrahepatic synthesis, 196, 197 

 extrahepatic utilization, 198, 199 

 from acetic acid, 83-87, 129 

 from amino acids, 130, 132-136 

 from branched-chain acids, 130, 131 

 from butyric acid, 126, 128 

 from dicarboxylic acids, 138, 139 

 from muconic acid, 338, 341 

 from odd-chahi acids, 128-130 

 from pyruvate, 136-138, 260, 261 

 in alkalosis, 142, 143 

 in diabetic cats, 82 

 in liver, 193, 194 

 in long-chain acids oxidation, 81 

 in multiple alternate oxidation, 80 

 in unsaturated acids oxidation, 95, 96, 



98 

 in vitro, 79, 80, 83, 84, 101, 125, 126 

 metabolism, 120-183 

 sources, 124-139 

 utilization in diabetes, 119 

 Ketonemia (see Ketosis) 

 Ketones, unsaturated, metabolism of, 100 

 Ketonuria, 78, 80, 85, 120, 121 

 adaptation to, 158-160 

 conditions resulting in, 139-146 

 diabetes, 140-142 

 « experimental, 143-146 



fasting, 139, 140 

 protein-fat diet, 140 

 effect of carbohydrates on, 163-180 



of glycerol on, 45 

 factors altering the extent of, 146-163 

 age, 154, 155 

 diet, 157, 158 

 hormones, 160-163 

 sex, 155, 156 

 species, 146-154 

 fatty acids: glucose ratio and, 122-124 

 succinic acid and, 127 

 jS-Ketooctanoic acid, oxidation, 303 

 /3-Ketooctanoyl-OoA, 107 



