570 



BACTERIOPHAGES 



Bacteria {continued) 



X-rays effect on, 177, 245, 246, 



312 

 Bacteriocins, 381-93; see also Colicins: 



Megacins; Pyocins 

 comparison with bacteriophages, 



392, 393 

 definition, 382 



eff"ect on results of phage typing, 403 

 Bacteriophage(s), see also Prophage; 



Temperate phage; Vegetative 



phage; and specific phages, e.g., 



Coliphage T2 

 adsorption to host cell, 15, 16, 23. 



24,77,123, 124,137-60 

 inhibition, 267-70 

 mutations aff"ecting, 298, 299, 



301,302 

 antibiotic action of, 2, 125 

 antigenic properties, 97-1 19, 422, 



423 

 assay, 27-34, 450-54 

 chemical composition, 83-95 

 comparison with animal and plant 



viruses, 6, 8, 433-35 

 comparison with bacteriocins, 381- 



83, 386, 387, 392, 393 

 concentration and purification, 42, 



83-85, 457-60 

 criteria of purity, 85-87 

 definition, 1, 2, 441 

 effect on bacterial hosts, 18, 19, 



165-68, 189-206 

 effect on induction of enzymes in 



host cell, 242, 243 

 epidemiological use, 395-420 



technique for, 404, 405 

 fate of constituents during infec- 

 tion, 207-31 

 genetic studies, 331-64 

 host specificity, 121-35 



mutations affecting, 298, 299, 



301,302 



and immunity to disease, 3 

 inactivation, 49-82 

 isolation, 447-49 

 labeled, preparation, 207 

 metabolic enzymes in, 237-40 

 morphology, 35-41, 164, 182-86 

 mutations, 16, 24, 116, 129-32, 



297-318, 501-11 

 nature of, 4-6 

 origin, 6-8 

 phenotypic modification, 132-35, 



291-97 

 preparation of stocks, 454-57 

 reactivation, 70-73, 76, 77, 82, 101, 



102, 357-64 

 related, definition, 12 



mixed infection with, 326-30 

 reproduction, 13-25, 161-87, 517- 

 22 

 inhibition, 265-87 

 mixed infection effect on, 319-30 

 nutritional and metabolic re- 

 quirements for, 233-64 

 size, 37-48, 423, 426 



elTect on plaque size, 23 

 species of, 422 

 taxonomy and taxonomic criteria, 



11, 12,421-37 

 techniques for study, 443-522 

 therapeutic applications, 3, 4 

 type-determining, 408-12, 415, 416, 



418 

 type specimens, 435-37 

 Bacteriophage ghosts, see Ghosts 

 Benzyldodecyldimethylammonium 

 chloride, effect on coliphage 

 T6,51 

 Benzyl-3-methyl tryptophan, in ad- 

 sorption of coliphage T4, 144 

 5-Bromouracil, in DNA of coliphage 



T2, 284, 316 

 Broth, effect on inactivation of bacte- 

 riophages, 58, 75, 454 



