Pfizer Handbook of Microbial Metabolites 



34 



Aspergillus niger 



Stanley Peat, W. J. Whelan and Kathleen A. Hinson, Chem. 

 and Ind., 385 (1955). 



A. Sato and K. Aso, Nature 180 984 (1957). 



43 Trehalose (Mycose, a-D-Glucosido-a-D-glucoside), CioHooOu, 

 colorless, hygroscopic crystals, m.p. ~210° (dec.) (anhy- 

 drous), 97° (hydrate), [<x]t>-° (hydrate) +178° (in water). 



CH2OH 



Amanita muscaria, other mushrooms and molds, myco- 

 bacteria, yeasts and algae. First isolated from rye ergot 

 (Claviceps purpurea (Fr. ) Tul.). 



Trehalose is present in young mushrooms, but as the 

 plants develop it is replaced by mannitol. It also occurs 

 in seaweeds and higher plants. 



E. Bourquelot, Compt. rend. 108 568 (1889). 



H. Bredereck, Ber. 63B 959 (1930). (Structure) 



Bengt Lindberg, Acta Chem. Scand. 9 917 (1955). 



44 Lactobionic Acid, CioHooOja, Calcium Salt : granular white pow- 

 der, [a],r' +25.1° (c 5.2 in water). 



COOH 



HCOH 



- I 

 HOCH 



HC 



CH— 



I 

 HCOH 



I 



HOCH 

 HOCH 

 HC 



HCOH 



I I 



CH2OH CH2OH 



Pseudomonas species, other oxidative bacteria (on lac- 

 tose) 



A 77 '^f yield has been reported. Maltobionic acid was 

 prepared similarly from maltose. 



Frank H. Stodola and Lewis B. Lockwood, J. Biol. Chem. 

 171 213 (1947). 



